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Adapalene 1 mg/g Gel — NDC 00363-4110-16 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Adapalene 1 mg/g Gel — NDC 0363-4110-16 (Billing 00363-4110-16)

by Walgreens · 1 TUBE in 1 CARTON / 45 g in 1 TUBE

This is a package of Adapalene 1 mg/g Gel from Walgreens, marketed since Jul 2025 and currently FDA-listed.

NDC 00363-4110-16
🏷️ FDA NDC (as labeled) 0363-4110-16 billing pads the labeler segment with a zero
This package
Contains45 g in 1 tube Pack sizes2 compare ↓
Product page 00363-4110-05 Also comes in: 15 g 0363-4110-05
OTC Generic On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Sep 10, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 0363-4110-16 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
0363 labeler · 4110 product · 16 package
Package marketed since
Jul 1, 2025
Sample package
No — commercial package
Listing certified through
Dec 31, 2027
Barcode (UPC)
0049022726970
FDA record last changed
Sep 10, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 0363-4110-16
Product NDC 0363-4110
11-digit billing NDC 00363411016
RxCUI 307731
UNII 1L4806J2QF
UPC 0049022726970
Application # ANDA090962
SPL Set ID 2c1cdc03-087d-43b0-b0b3-503a35398a53
Established class (EPC) Retinoid
Chemical class Retinoids
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2025-07-01
Route TOPICAL
Dosage form GEL
Substance ADAPALENE
Quick answers
  • RxCUI (RxNorm): 307731
Why two NDCs? The FDA registers this code as 0363-4110-16 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00363-4110-16. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Retinoid class.

Pharmacologic class Retinoid
Drug family (ATC) Retinoids for topical use in acne
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📗 Our plain-language guide HelloPharmacist
  • It treats acne vulgaris, the common type of acne. Some products are labeled for ages 12 and up. Ask a doctor before using it in younger children.
  • Use it once a day, usually in the evening, on clean, dry skin. Apply a thin layer to the whole affected area and keep it away from your eyes, lips and inside of your mouth or nose....
  • Give it about 8 to 12 weeks. Acne can seem to flare in the early weeks, which is not a reason to stop. If you see no improvement after 12 weeks, talk to your prescriber.
  • Redness, dryness, peeling and some burning or stinging are the most common, especially in the first month. They are usually mild to moderate and often ease. A moisturizer can help....
📖 Read our full Adapalene guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer gPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 15 g
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
00363-4110-05 0363-4110-05 Main listing 1 TUBE in 1 CARTON / 15 g in 1 TUBE 2025-07-01 — Active
00363-4110-16 You're viewing this 1 TUBE in 1 CARTON / 45 g in 1 TUBE 2025-07-01 — Active

Pack size FAQ

What quantity is in this package?
This package is listed by the FDA — 1 tube in 1 carton / 45 g in 1 tube.
What NDC number is used to bill for this package of Adapalene 1 mg/g Gel?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Adapalene 1 mg/g 00536-1412-20 RUGBY 1 tube $0.466 — Availability likely —
Adapalene 1 mg/g 46122-0768-36 AMERISOURCE 1 tube $0.466 — Availability likely —
Adapalene 1 mg/g 51672-2150-01 Sun 1 tube $0.466 — Availability likely —
Adapalene 1 mg/g 70000-0666-01 Cardinal 1 tube $0.466 — Availability likely —
Adapalene 1 mg/g 00168-0424-46 E. 1 tube $2.855 AB Availability likely —
Differin 1 mg/g 00299-4910-00 Galderma 1 tube — — FDA listed —
PanOxyl 1 mg/g 00316-0143-15 CROWN 1 tube — — FDA listed —
PanOxyl 1 mg/g 00316-0284-15 CROWN 1 tube — — FDA listed —
Adapalene 1 mg/g 00363-0888-05 Walgreens 1 tube — — FDA listed —
Adapalene 1 mg/g 00363-1401-05 Walgreens 1 tube — — FDA listed —
Adapalene 1 mg/gthis 00363-4110-16 Walgreens 1 tube — — FDA listed —
Proactiv MD Adapalene Acne Treatment .1 g/100g 11410-0958-15 Alchemee, 1 tube — — FDA listed —
Adapalene 1 mg/g 11822-0062-01 RITE 1 tube — — FDA listed —
Adapalene 1 mg/g 21130-0754-05 Safeway, 1 tube — — FDA listed —
Adapalene 1 mg/g 30142-0725-05 The 1 tube — — FDA listed —
Adapalene 1 mg/g 36800-0088-05 TOP 1 tube — — FDA listed —
Adapalene 1 mg/g 41250-0288-05 MEIJER, 1 tube — — FDA listed —
Adapalene 1 mg/g 49967-0354-01 LOreal 1 tube — — FDA listed —
Effaclar 1 mg/g 49967-0591-01 LOreal 1 tube — — FDA listed —
Effaclar 1 mg/g 49967-0592-01 LOreal 1 tube — — FDA listed —
Adapalene 1 mg/g 51316-0114-05 CVS 1 tube — — FDA listed —
Adapalene 1 mg/g 55910-0880-05 Dolgencorp, 1 tube — — FDA listed —
Adapalene 1 mg/g 59726-0114-05 P 1 tube — — FDA listed —
Adapalene 1 mg/g 59726-0888-05 P 1 tube — — Discontinued —
Adapalene 1 mg/g 69842-0088-05 CVS 1 tube — — FDA listed —
Neutrogena Adapalene 0.1% Acne Treatment 1 mg/g 69968-0826-01 Kenvue 1 tube — — FDA listed —
Neutrogena Evenly Clear Retinoid Adapalene Gel 0.1% Acne Treatment 1 mg/g 69968-0945-02 Kenvue 1 tube — — FDA listed —
Neutrogena Evenly Clear Retinoid Adapalene Gel 0.1% Acne Treatment 1 mg/g 69968-1004-02 Kenvue 1 tube — — FDA listed —
Curist Acne Relief .1 g/100g 72559-0015-13 Little 1 tube — — FDA listed —
Adapalene 1 mg/g 72657-0158-15 GLENMARK 1 bottle — — FDA listed —
Adapalene 1 mg/g 73581-0019-06 YYBA 1 tube — — FDA listed —
Adapalene 1 mg/g 73581-0214-06 YYBA 1 tube — — FDA listed —
Adapalene 1 mg/g 73581-0215-45 YYBA 1 tube — — FDA listed —
Adapalene 1 mg/g 73581-0216-45 YYBA 1 tube — — FDA listed —
Adapalene Gel 0.1% .1 g/100g 73715-0003-01 MOHNARK 30 g — — Discontinued —
Adapalene 1 mg/g 76162-0114-05 Topco 1 tube — — FDA listed —
Adapalene 1 mg/g 79481-1140-05 Meijer 1 tube — — FDA listed —
Adapalene 1 mg/g 79903-0338-05 Wal-Mart 1 tube — — FDA listed —
Adapalene 1 mg/g 82442-0105-01 Target 1 tube — — FDA listed —
Adapalene 1 mg/g 72162-1048-02 Bryant 1 tube — AB FDA listed —
Adapalene 1 mg/g 63629-8791-01 Bryant 1 tube — AB FDA listed —
Adapalene Paraben Free 1 mg/g 76162-0221-05 Topco 1 tube — — FDA listed —
Adapalene Paraben Free 1 mg/g 79481-2210-05 Meijer 1 tube — — FDA listed —
Adapalene Paraben Free 1 mg/g 30142-0542-05 The 1 tube — — FDA listed —
Adapalene Paraben Free 1 mg/g 51316-0219-05 CVS 1 tube — — FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2025
On the market since
Jul 2025
📍
2026
Currently FDA-listed
1 year listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Adapalene inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerWalgreens
Application holderP AND L DEVELOPMENT LLC
FDA applicationANDA090962 (ANDA)
Labeler code00363
First marketedJul 2025
Product typeHuman Otc Drug
Portfolio342 products on file

More NDCs from Walgreens labeler code 00363

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 6 words ▾

Use For the treatment of acne

⏱️ Dosage and Administration 84 words ▾

Directions Adults and children 12 years of age and older: use once daily clean the skin gently and pat dry before applying the product cover the entire affected area with a thin layer. For example, if your acne in on the face, apply the product to the entire face. do not use more than one time a day. Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age : ask a doctor

⚠️ Warnings ~1 min read ▾

Warnings For external use only Do not use on damaged skin (cuts, abrasions eczema, sunburn) if you are allergic to adapalene or any of the ingredients in this product Pregnancy/Breastfeeding, ask a doctor before use. When using this product limit sun exposure, including light from tanning beds, and use sunscreen when going outdoors. do not wax to remove hair in areas where the product has been applied during the early weeks of use, your acne may appear to worsen before it improves (this is normal); continue using as directed, unless you get irritation that become severe irritation (redness, itching, dryness, burning) is more likely to occur: in the first few weeks of use if using more than one topical acne medication at a time but irritation usually lessens with continued use of this product it may take up to 3 months of once daily use to see result avoid product contact eyes, lips, and month.

If contact occurs immediately flush the area with water. wash hands after use Stop use and ask a doctor if you become pregnant, or planning to become pregnant while using this product you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath) irritation become severe you see no improvement after 3 months of once daily use Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

🧪 Active Ingredient 10 words ▾

Active ingredient Adapalene USP 0.1% (retinoid)* *read consumer information leaflet

🧪 Inactive Ingredients 24 words ▾

Inactive ingredients carbomer homopolymer typeC, edetate disodium, methylparabem, poloxamer 182, propylene glycol, purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

🎯 Purpose 3 words ▾

Purpose Acne treatment

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Adapalene — the program that covers self-administered drugs. 8 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Adapalene. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$999.6K
Claims incl. refills
2.4K
Beneficiaries
1.8K
Spend / beneficiary
$553.81
Spend / claim
$410.69
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Walgreens. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 1 tube (00363-4110-05). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Walgreens is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 00363-4101-13 · Walgreen 00363-4115-28 · Walgreen →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.