Glyburide 2.5 MG / metformin hydrochloride 500 MG Oral Tablet — RxCUI 861748
RxNorm drug concept · Semantic clinical drug
RxCUI 861748
Semantic clinical drug · SCD
● Current RxNorm concept 20 FDA products
77 package NDCs
Snapshot Jul 14, 2026
What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.
🗂️ Key Facts
RxCUI861748
Official nameGlyburide 2.5 MG / metformin hydrochloride 500 MG Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asglyBURIDE 2.5 MG / metFORMIN HCl 500 MG Oral Tablet
FDA products mapped20
Package NDCs mapped77
Reported Medicaid activity (SDUD)16,761 prescriptions · 32 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026
📖 Skip the Codes — Read It in Plain English.
Our pharmacist-built guide to Glyburide: what it is, how it’s used, side effects, and interactions.
📗 Our plain-language guide HelloPharmacist
- It helps control blood sugar in adults with type 2 diabetes. It works alongside healthy eating and exercise, not in place of them.
- Take it by mouth, usually with breakfast or your first main meal. Many people take it once a day, but some split it into two doses. Follow your prescriber's directions and the phar...
- Low blood sugar. Skipping meals or not following your plan can bring it on. If you get confusion, seizures or pass out, that's an emergency and you need immediate care.
- What is the biggest side effect to watch for?
🕸️ Concept Web — How Glyburide 2.5 MG / metformin hydrochloride 500 M... Connects
One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept
Glyburide 2.5 MG / metformin hydrochloride 500 MG Oral Tablet
RxCUI 861748 Semantic clinical drug · SCD
Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.
-
Ingredients 4
The active substance itself — no strength, form, or brand attached yet.
-
Glyburide
4815IN -
Metformin
6809IN -
Glyburide / metformin
285129MIN -
Metformin hydrochloride
235743PIN
-
Glyburide
-
Dose forms 9
The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.
-
Glyburide / metformin Oral Tablet
374635SCDF -
Glyburide / metformin hydrochloride Oral Tablet
2646768SCDFP -
Glyburide / metformin Oral Product
1165845SCDG -
Glyburide / metformin Pill
1156197SCDG -
Glyburide / metformin hydrochloride Oral Product
2659882SCDGP -
Glyburide / metformin hydrochloride Pill
2663215SCDGP -
Oral Tablet
317541DF -
Oral Product
1151131DFG - +1 more in this family
-
Glyburide / metformin Oral Tablet
-
Clinical & branded drugs 2
Ingredient + strength + dose form. These are the concepts real FDA products actually carry.
-
Glyburide 2.5 MG
315989SCDC -
Metformin hydrochloride 500 MG
860974SCDC
-
Glyburide 2.5 MG
Showing up to 8 concepts per family — 14 of 15 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.
🔀 Generic ⇄ Brand Crosswalk
The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.
Generic (Clinical) Concepts
-
Glyburide 2.5 MG
SCDC · 315989 -
Metformin hydrochloride 500 MG
SCDC · 860974 -
Glyburide / metformin Oral Tablet
SCDF · 374635 -
Glyburide / metformin hydrochloride Oral Tablet
SCDFP · 2646768 -
Glyburide / metformin Oral Product
SCDG · 1165845 -
Glyburide / metformin Pill
SCDG · 1156197 -
Glyburide / metformin hydrochloride Oral Product
SCDGP · 2659882 -
Glyburide / metformin hydrochloride Pill
SCDGP · 2663215
📦 FDA Products & Package NDCs
20 products · 77 package NDCs
77 package NDCs map to RxCUI 861748 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
| Package NDC | Package | Brand / generic name | Labeler | Marketing start |
|---|---|---|---|---|
| 23155-0233-01 | 100 TABLET in 1 BOTTLE (23155-233-01) | glyburide-metformin hydrochloride | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2024-05-01 |
| 23155-0233-05 | 500 TABLET in 1 BOTTLE (23155-233-05) | glyburide-metformin hydrochloride | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2024-05-01 |
| 23155-0233-10 | 1000 TABLET in 1 BOTTLE (23155-233-10) | glyburide-metformin hydrochloride | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2024-05-01 |
| 23155-0234-01 | 100 TABLET in 1 BOTTLE (23155-234-01) | glyburide-metformin hydrochloride | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2024-05-01 |
| 23155-0234-05 | 500 TABLET in 1 BOTTLE (23155-234-05) | glyburide-metformin hydrochloride | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2024-05-01 |
| 23155-0234-10 | 1000 TABLET in 1 BOTTLE (23155-234-10) | glyburide-metformin hydrochloride | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2024-05-01 |
| 23155-0235-01 | 100 TABLET in 1 BOTTLE (23155-235-01) | glyburide-metformin hydrochloride | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2024-05-01 |
| 23155-0235-05 | 500 TABLET in 1 BOTTLE (23155-235-05) | glyburide-metformin hydrochloride | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2024-05-01 |
| 23155-0235-10 | 1000 TABLET in 1 BOTTLE (23155-235-10) | glyburide-metformin hydrochloride | Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2024-05-01 |
| 50090-2030-00 | 60 TABLET, FILM COATED in 1 BOTTLE (50090-2030-0) | Glyburide and Metformin Hydrochloride | A-S Medication Solutions | 2015-09-24 |
| 50090-2030-02 | 100 TABLET, FILM COATED in 1 BOTTLE (50090-2030-2) | Glyburide and Metformin Hydrochloride | A-S Medication Solutions | 2015-09-24 |
| 50090-2030-03 | 90 TABLET, FILM COATED in 1 BOTTLE (50090-2030-3) | Glyburide and Metformin Hydrochloride | A-S Medication Solutions | 2015-09-24 |
| 50090-2030-04 | 180 TABLET, FILM COATED in 1 BOTTLE (50090-2030-4) | Glyburide and Metformin Hydrochloride | A-S Medication Solutions | 2015-09-24 |
| 50090-2031-00 | 60 TABLET, FILM COATED in 1 BOTTLE (50090-2031-0) | Glyburide and Metformin Hydrochloride | A-S Medication Solutions | 2015-09-24 |
| 50090-2031-02 | 180 TABLET, FILM COATED in 1 BOTTLE (50090-2031-2) | Glyburide and Metformin Hydrochloride | A-S Medication Solutions | 2015-09-24 |
| 50090-7814-00 | 60 TABLET in 1 BOTTLE (50090-7814-0) | glyburide-metformin hydrochloride | A-S Medication Solutions | 2025-12-09 |
| 50090-7814-02 | 180 TABLET in 1 BOTTLE (50090-7814-2) | glyburide-metformin hydrochloride | A-S Medication Solutions | 2025-12-09 |
| 57237-0023-01 | 100 TABLET, FILM COATED in 1 BOTTLE (57237-023-01) | Glyburide and Metformin Hydrochloride | Rising Pharma Holdings, Inc. | 2007-11-14 |
| 57237-0023-05 | 500 TABLET, FILM COATED in 1 BOTTLE (57237-023-05) | Glyburide and Metformin Hydrochloride | Rising Pharma Holdings, Inc. | 2007-11-14 |
| 57237-0024-01 | 100 TABLET, FILM COATED in 1 BOTTLE (57237-024-01) | Glyburide and Metformin Hydrochloride | Rising Pharma Holdings, Inc. | 2007-11-14 |
| 57237-0024-05 | 500 TABLET, FILM COATED in 1 BOTTLE (57237-024-05) | Glyburide and Metformin Hydrochloride | Rising Pharma Holdings, Inc. | 2007-11-14 |
| 57237-0025-01 | 100 TABLET, FILM COATED in 1 BOTTLE (57237-025-01) | Glyburide and Metformin Hydrochloride | Rising Pharma Holdings, Inc. | 2007-11-14 |
| 57237-0025-05 | 500 TABLET, FILM COATED in 1 BOTTLE (57237-025-05) | Glyburide and Metformin Hydrochloride | Rising Pharma Holdings, Inc. | 2007-11-14 |
| 65841-0824-01 | 100 TABLET in 1 BOTTLE (65841-824-01) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0824-05 | 500 TABLET in 1 BOTTLE (65841-824-05) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0824-06 | 30 TABLET in 1 BOTTLE (65841-824-06) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0824-10 | 1000 TABLET in 1 BOTTLE (65841-824-10) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0824-16 | 90 TABLET in 1 BOTTLE (65841-824-16) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0824-77 | 10 BLISTER PACK in 1 CARTON (65841-824-77) / 10 TABLET in 1... | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0825-01 | 100 TABLET in 1 BOTTLE (65841-825-01) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0825-05 | 500 TABLET in 1 BOTTLE (65841-825-05) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0825-06 | 30 TABLET in 1 BOTTLE (65841-825-06) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0825-10 | 1000 TABLET in 1 BOTTLE (65841-825-10) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0825-16 | 90 TABLET in 1 BOTTLE (65841-825-16) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0825-77 | 10 BLISTER PACK in 1 CARTON (65841-825-77) / 10 TABLET in 1... | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0826-01 | 100 TABLET in 1 BOTTLE (65841-826-01) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0826-05 | 500 TABLET in 1 BOTTLE (65841-826-05) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0826-06 | 30 TABLET in 1 BOTTLE (65841-826-06) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0826-10 | 1000 TABLET in 1 BOTTLE (65841-826-10) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0826-16 | 90 TABLET in 1 BOTTLE (65841-826-16) | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65841-0826-77 | 10 BLISTER PACK in 1 CARTON (65841-826-77) / 10 TABLET in 1... | glyburide and metformin hydrochloride | Zydus Lifesciences Limited | 2016-04-07 |
| 65862-0080-01 | 100 TABLET, FILM COATED in 1 BOTTLE (65862-080-01) | Glyburide and Metformin Hydrochloride | Aurobindo Pharma Limited | 2007-11-14 |
| 65862-0080-05 | 500 TABLET, FILM COATED in 1 BOTTLE (65862-080-05) | Glyburide and Metformin Hydrochloride | Aurobindo Pharma Limited | 2007-11-14 |
| 65862-0080-30 | 30 TABLET, FILM COATED in 1 BOTTLE (65862-080-30) | Glyburide and Metformin Hydrochloride | Aurobindo Pharma Limited | 2007-11-14 |
| 65862-0081-01 | 100 TABLET, FILM COATED in 1 BOTTLE (65862-081-01) | Glyburide and Metformin Hydrochloride | Aurobindo Pharma Limited | 2007-11-14 |
| 65862-0081-05 | 500 TABLET, FILM COATED in 1 BOTTLE (65862-081-05) | Glyburide and Metformin Hydrochloride | Aurobindo Pharma Limited | 2007-11-14 |
| 65862-0081-30 | 30 TABLET, FILM COATED in 1 BOTTLE (65862-081-30) | Glyburide and Metformin Hydrochloride | Aurobindo Pharma Limited | 2007-11-14 |
| 65862-0082-01 | 100 TABLET, FILM COATED in 1 BOTTLE (65862-082-01) | Glyburide and Metformin Hydrochloride | Aurobindo Pharma Limited | 2007-11-14 |
| 65862-0082-05 | 500 TABLET, FILM COATED in 1 BOTTLE (65862-082-05) | Glyburide and Metformin Hydrochloride | Aurobindo Pharma Limited | 2007-11-14 |
| 65862-0082-30 | 30 TABLET, FILM COATED in 1 BOTTLE (65862-082-30) | Glyburide and Metformin Hydrochloride | Aurobindo Pharma Limited | 2007-11-14 |
Observed labelers:
Zydus Lifesciences Limited (18) ·
Zydus Pharmaceuticals (USA) Inc. (18) ·
Aurobindo Pharma Limited (9) ·
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. (9) ·
A-S Medication Solutions (8) ·
Rising Pharma Holdings, Inc. (6)
· +2 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.
🗃️ Sources & Limits
Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
- A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
- Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
- Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
- Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.