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Esomeprazole 20 MG / naproxen 375 MG Delayed Release Oral Tablet — RxCUI 994005

RxNorm drug concept · Semantic clinical drug
RxCUI 994005 Semantic clinical drug · SCD ● Current RxNorm concept 10 FDA products 22 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI994005
Official nameEsomeprazole 20 MG / naproxen 375 MG Delayed Release Oral Tablet
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asesomeprazole (as esomeprazole magnesium) 20 MG / naproxen (as naproxen sodium) 375 MG Delayed Release Oral Tablet; naproxen 375 MG / esomeprazole magnesium 20 MG Delayed Release Oral Tablet
FDA products mapped10
Package NDCs mapped22
Reported Medicaid activity (SDUD)2,982 prescriptions · 3 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Esomeprazole Injection: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • The IV form is used when you can't swallow or absorb oral medication — for example, if you're recovering from a procedure, having surgery, or are too unwell to take anything by mou...
  • Why am I getting esomeprazole through an IV instead of just taking a pill?
  • That depends on what it's being used for. For GERD with esophagitis, it's approved for up to 10 days via IV — and your team will move you to oral esomeprazole as soon as possible....
  • How long will I be on this IV medication?
📖 Read our full Esomeprazole Injection guide →

🕸️ Concept Web — How Esomeprazole 20 MG / naproxen 375 MG Delayed Rel... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Esomeprazole 20 MG / naproxen 375 MG Delayed Release Oral Tablet RxCUI 994005

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 3

    The active substance itself — no strength, form, or brand attached yet.

    • Esomeprazole 283742
    • Naproxen 7258
    • Esomeprazole / naproxen 994202
  2. Brand names 1

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Vimovo 1372705
  3. Dose forms 9

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Esomeprazole / naproxen Delayed Release Oral Tablet 977953
    • Esomeprazole / naproxen Oral Product 1164523
    • Esomeprazole / naproxen Pill 1164524
    • Esomeprazole / naproxen Delayed Release Oral Tablet [Vimovo] 977957
    • Vimovo Oral Product 1186604
    • Vimovo Pill 1186607
    • Delayed Release Oral Tablet 10312
    • Oral Product 1151131
    • +1 more in this family
  4. Clinical & branded drugs 4

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

    • Esomeprazole 20 MG 343355
    • Naproxen 375 MG 316327
    • Esomeprazole 20 MG / naproxen 375 MG Delayed Release Oral Tablet [Vimovo] 994007
    • Esomeprazole 20 MG / naproxen 375 MG [Vimovo] 994006

Showing up to 8 concepts per family — 16 of 17 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Esomeprazole 20 MG SCDC · 343355
  • Naproxen 375 MG SCDC · 316327
  • Esomeprazole / naproxen Delayed Release Oral Tablet SCDF · 977953
  • Esomeprazole / naproxen Oral Product SCDG · 1164523
  • Esomeprazole / naproxen Pill SCDG · 1164524

Brand-Name Concepts

  • Esomeprazole 20 MG / naproxen 375 MG Delayed Release Oral Tablet [Vimovo] SBD · 994007
  • Esomeprazole 20 MG / naproxen 375 MG [Vimovo] SBDC · 994006
  • Esomeprazole / naproxen Delayed Release Oral Tablet [Vimovo] SBDF · 977957
  • Vimovo Oral Product SBDG · 1186604
  • Vimovo Pill SBDG · 1186607
  • Vimovo BN · 1372705

📦 FDA Products & Package NDCs

10 products · 22 package NDCs
22 package NDCs map to RxCUI 994005 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
27241-0202-60 60 TABLET, DELAYED RELEASE in 1 BOTTLE (27241-202-60) Naproxen and esomeprazole magnesium Ajanta Pharma USA Inc. 2022-10-06
27241-0203-60 60 TABLET, DELAYED RELEASE in 1 BOTTLE (27241-203-60) Naproxen and esomeprazole magnesium Ajanta Pharma USA Inc. 2022-10-06
50228-0437-10 1000 TABLET, DELAYED RELEASE in 1 BOTTLE (50228-437-10) Naproxen and esomeprazole magnesium ScieGen Pharmaceuticals, Inc 2023-10-11
50228-0437-30 30 TABLET, DELAYED RELEASE in 1 BOTTLE (50228-437-30) Naproxen and esomeprazole magnesium ScieGen Pharmaceuticals, Inc 2023-10-11
50228-0437-60 60 TABLET, DELAYED RELEASE in 1 BOTTLE (50228-437-60) Naproxen and esomeprazole magnesium ScieGen Pharmaceuticals, Inc 2024-03-12
50228-0438-05 500 TABLET, DELAYED RELEASE in 1 BOTTLE (50228-438-05) Naproxen and esomeprazole magnesium ScieGen Pharmaceuticals, Inc 2023-10-11
50228-0438-30 30 TABLET, DELAYED RELEASE in 1 BOTTLE (50228-438-30) Naproxen and esomeprazole magnesium ScieGen Pharmaceuticals, Inc 2023-10-11
50228-0438-60 60 TABLET, DELAYED RELEASE in 1 BOTTLE (50228-438-60) Naproxen and esomeprazole magnesium ScieGen Pharmaceuticals, Inc 2024-03-12
55111-0289-60 60 TABLET, DELAYED RELEASE in 1 BOTTLE (55111-289-60) Naproxen and esomeprazole magnesium Dr. Reddy's Laboratories Limited 2020-02-18
55111-0701-60 60 TABLET, DELAYED RELEASE in 1 BOTTLE (55111-701-60) Naproxen and esomeprazole magnesium Dr. Reddy's Laboratories Limited 2020-02-18
68788-8906-03 30 TABLET, DELAYED RELEASE in 1 BOTTLE (68788-8906-3) Naproxen and esomeprazole magnesium Preferred Pharmaceuticals Inc 2025-07-31
68788-8906-06 60 TABLET, DELAYED RELEASE in 1 BOTTLE (68788-8906-6) Naproxen and esomeprazole magnesium Preferred Pharmaceuticals Inc 2025-07-31
76420-0889-01 100 TABLET, DELAYED RELEASE in 1 BOTTLE (76420-889-01) Naproxen and esomeprazole magnesium Asclemed USA, Inc. 2024-12-28
76420-0889-30 30 TABLET, DELAYED RELEASE in 1 BOTTLE (76420-889-30) Naproxen and esomeprazole magnesium Asclemed USA, Inc. 2024-12-28
76420-0889-60 60 TABLET, DELAYED RELEASE in 1 BOTTLE (76420-889-60) Naproxen and esomeprazole magnesium Asclemed USA, Inc. 2024-12-28
76420-0889-90 90 TABLET, DELAYED RELEASE in 1 BOTTLE (76420-889-90) Naproxen and esomeprazole magnesium Asclemed USA, Inc. 2024-12-28
76420-0890-01 100 TABLET, DELAYED RELEASE in 1 BOTTLE (76420-890-01) Naproxen and esomeprazole magnesium Asclemed USA, Inc. 2024-12-28
76420-0890-30 30 TABLET, DELAYED RELEASE in 1 BOTTLE (76420-890-30) Naproxen and esomeprazole magnesium Asclemed USA, Inc. 2024-12-28
76420-0890-60 60 TABLET, DELAYED RELEASE in 1 BOTTLE (76420-890-60) Naproxen and esomeprazole magnesium Asclemed USA, Inc. 2024-12-28
76420-0890-90 90 TABLET, DELAYED RELEASE in 1 BOTTLE (76420-890-90) Naproxen and esomeprazole magnesium Asclemed USA, Inc. 2024-12-28
85509-1202-03 30 TABLET, DELAYED RELEASE in 1 BOTTLE (85509-1202-3) Naproxen and esomeprazole magnesium PHOENIX RX LLC 2025-07-21
85509-1202-06 60 TABLET, DELAYED RELEASE in 1 BOTTLE (85509-1202-6) Naproxen and esomeprazole magnesium PHOENIX RX LLC 2025-07-21
Observed labelers: Asclemed USA, Inc. (8) · ScieGen Pharmaceuticals, Inc (6) · Ajanta Pharma USA Inc. (2) · Dr. Reddy's Laboratories Limited (2) · PHOENIX RX LLC (2) · Preferred Pharmaceuticals Inc (2) — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.