Can You Take Eliquis And Ashwagandha Together?

In our latest question and answer, the pharmacist discusses the combined use of ashwagandha and Eliquis.


Is it safe to consume ashwagandha and Eliquis daily but at different times?

Asked by geri On Apr 12, 2024

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Apr 12, 2024
Last updated May 20, 2024


Thank you for reaching out! It's always very important to look into potential interactions between prescription medications and over-the-counter supplements, particularly for individuals taking anticoagulants or other medications that affect blood clotting, so I'm happy to answer this for you.

While our herbal interaction checker highlights several potential interactions between ashwagandha and prescription/over-the-counter medications, we do not currently list an interaction between Eliquis and ashwagandha (Ashwagandha - Apixaban Interaction Details | HelloPharmacist).

There is currently no documented evidence indicating that ashwagandha, at typical supplement doses, has a clinically significant effect on blood coagulation in humans.

While some studies have reported a very minor antiplatelet effect with ashwagandha, this has only been observed in laboratory studies or in animals receiving very high doses of the herb.

Furthermore, there is no evidence to suggest that it interacts with Eliquis in a clinically significant manner. So, to answer your question specifically, I could find no evidence that Eliquis and ashwagandha are unsafe together.

It's important to note, however, that there is a lack of specific studies evaluating the combined use of ashwagandha and Eliquis. I couldn't find a single one. Therefore, just to be safe, caution is advised, and consulting your doctor before making any changes to your medication regimen is important to do.

Final Words

In summary, while no interaction between ashwagandha and Eliquis is expected based on current knowledge, it's important to let your doctor know about the medication changes you are considering so you can be appropriately monitored.


  • Adaptogenic and cardioprotective action of ashwagandha in rats and frogs, PubMed
  • An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study, PubMed

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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