Is Zinc Safe To Take With Eliquis?

In our latest question and answer, the pharmacist discusses the safety of taking zinc with Eliquis.

1 min read Updated Jun 2026 Read by 2,775 people
Is Zinc Safe To Take With Eliquis?
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Nick asked

Can I take zinc while taking Eliquis (apixaban)?

Jan 31, 2025
The quick answer
  • Zinc does not interact with Eliquis, so it appears safe to take them together.
  • As always, check with your doctor before adding any new supplement to your current medications.
A quick summary of Dr. Brian Staiger, PharmD's full answer below, condensed by AI from that answer only (not from any outside source). The pharmacist's answer is the source of record.
Medications in this answer — tap to explore

Answer

Thank you for reaching out!

This is an excellent question! Zinc is very important to look into before adding to your medication regimen as it is known to have very impactful interactions. For example, zinc is well known to interact with various antibiotics, such as cephalexin—which may reduce their absorption and effectiveness. For more detailed information on the interaction between zinc and cephalexin (which is applicable to many different antibiotics), please see our page on this interaction: Zinc - Cephalexin Interaction Details | HelloPharmacist.

Fortunately, there are no known interactions between zinc and Eliquis (apixaban). Zinc does not chelate with Eliquis, and current evidence indicates that taking a zinc supplement together with Eliquis is safe. You can find more details on this here: Zinc - Apixaban Interaction Details | HelloPharmacist.

If you are considering taking a zinc supplement, it appears to be safe to combine it with Eliquis but as always, be sure to consult with your doctor before adding on any drugs or supplements to your medication regimen.

Final Words

Thank you again for reaching out. Please feel free to contact us anytime with further questions!

References & sources
  1. The effect of staggered administration of zinc sulfate on the pharmacokinetics of oral cephalexin — PubMed
  2. Eliquis Prescribing Information — BMS
Glossary — Terms in This Answer
Medication regimen
The complete set of medications and supplements a person takes on a regular schedule.
Interactions
Changes in how medications work when taken together, which can increase or decrease their effectiveness.
Antibiotics
Medicines used to treat infections caused by bacteria.
Cephalexin
A type of antibiotic medication used to treat bacterial infections.
Absorption
The process by which a medication enters the bloodstream from the digestive system.
Apixaban
A blood-thinning medication (brand name Eliquis) used to prevent blood clots.
Chelate
To bind to or trap a substance in a way that prevents it from being absorbed or used by the body.
Supplement
A product taken by mouth that contains vitamins, minerals, or other substances intended to add to the diet.
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Dr. Brian Staiger, PharmD
About the pharmacist

Dr. Brian Staiger, PharmD

Clinical Pharmacy

Doctor of Pharmacy, board certified clinical pharmacist (BCPS), American Herbalist Guild, Medication Therapy Management certified

Brian Staiger, PharmD, BCPS, is a licensed pharmacist with more than 13 years of experience across retail pharmacy, clinical pharmacy, medication safety, pharmacy program development, and healthcare administration. He is the founder of HelloPharmacist.com, where he helps patients...

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