Can You Take Eliquis With Bromelain?

Quick Answer

Taking bromelain in combination with Eliquis, an anticoagulant drug, may increase the risk of bleeding. It is recommended to exercise caution and consult with your healthcare provider before starting bromelain if you are taking Eliquis.

Detailed Answer

Bromelain, a proteolytic enzyme, has the potential to inhibit platelet aggregation, which 'thins' the blood. Eliquis (apixaban) is classified as an anticoagulant, which also 'thins' the blood. Therefore, combining bromelain with Eliquis can increase the risk of bleeding. This interaction is detailed in our 'drug-herbal interaction checker'.

It is important to note that there is extremely limited information available on this specific interaction. However, there is at least one case report of minor bruising in a patient taking bromelain with naproxen, a non-steroidal anti-inflammatory drug, and lab studies show that bromelain does appear to have at least very mild 'blood thinning' actions (here is a lab study reporting its antiplatelet effects).

Observational research suggests that topical application of bromelain for wound debridement does not significantly affect coagulation markers. However, it is important to note that this research focused on topical use, and the interaction may differ when bromelain is taken orally.

How To Manage The Interaction

It's unlikely that bromelain significantly 'thins' the blood, but for an individual taking a drug like Eliquis, it just has the risk of increasing bleeding episodes.

If you are considering taking bromelain while on Eliquis, it is crucial to consult with your healthcare provider. They can assess your individual case and provide personalized advice.

If you do take bromelain and Eliquis together, be sure to watch out easy bruising/bleeding.

Final Words

The interaction between bromelain and Eliquis is not well-studied, and caution is advised. It is essential to involve your healthcare provider in the decision-making process to ensure your safety and reduce the risk of potential complications.

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