Can You Take Tessalon With Mucinex?

In our latest question and answer, the pharmacist discusses if it is safe to combine Tessalon (benzonatate) and Mucinex (guaifenesin).

Question

Is it okay to mix Tessalon and Mucinex together? I was prescribed Tessalon and forgot to ask about Mucinex.

Asked by Cato On Nov 04, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Nov 04, 2022
Last updated Apr 20, 2024

Key points

  • There is no known interaction between Tessalon (benzonatate) and Mucinex (guaifenesin).

Answer

There is no known interaction between Tessalon (brand for benzonatate) and Mucinex (guaifenesin). They are considered safe to take with one another.

It's not uncommon that these types of drugs (a cough suppressant and expectorant) are combined.

A similar combination to this would be dextromethorphan (generic for Delsym) and Mucinex. One drug helps to reduce the frequency and severity of coughing (dextromethorphan or benzonatate) while the other (guaifenesin) helps to thin and clear out mucus.

In addition to not having any interaction between them, Tessalon and Mucinex do not share many similar side effects and are, generally, very well tolerated.

What Is Tessalon?

Tessalon is a brand name drug that contains benzonatate and is used to relieve cough. Benzonatate is in a class of medications called antitussives (cough suppressants) and works by reducing the cough reflex in the lungs and air passages.

What Is Mucinex?

Mucinex contains guaifenesin and is used to relieve chest congestion. It is in a class of medications called expectorants. It works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.

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Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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