Taking Buspar (Buspirone) Once A Day Versus Multiple Times Per Day

In our latest question and answer, the pharmacist discusses dosing recommendations for the anti-anxiety medication Buspar (buspirone).

Question

I am taking 10mg of Buspar in the AM, as well as 20mg of Busbar and 10mg of Paxil in the PM. Can I take all these meds in the AM instead of splitting them up?

Asked by Chuck On Jul 26, 2022

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Jul 26, 2022
Last updated May 03, 2024

Key points

  • Buspar (buspirone) is typically dosed 2 to 3 times daily.
  • Taking a larger dose of Buspar at once won't make the drug last longer. Each doses generally lasts 4 to 8 hours.

Thanks for reaching out to us!

You should not combine your morning and evening doses of Buspar (buspirone). Buspar is indicated to be dosed two to three times a day and taking the entire dose at once in the morning will likely result in effects of the drug not lasting all day. It could also increase the risk of dose-dependent side effects, such as:

  • Dizziness
  • Drowsiness
  • Nervousness
  • Lightheadedness
  • Excitability
  • Anger/hostility
  • Confusion
  • Numbness
  • Headache
  • Incoordination

Buspar Dosing

Per the prescribing information for Buspar, it is indicated to be dosed as follows:

  • Starting dose of 7.5 mg by mouth twice daily, then increase as needed by 5 mg/day every 2 to 3 days. The usual maintenance dose is 15 to 30 mg/day administered in 2 to 3 divided doses

Effects of Buspar generally last 4-8 hours, but this can vary by individual. Increasing your dose in the morning will most likely not make it last longer, which is why the drug is recommended to take in divided doses throughout the day. Even if you take a larger dose at once, that won't make the drug last any longer.

Final Words

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References

  • Buspar Prescribing Information, AccessFDA
  • Buspirone: an update on a unique anxiolytic agent, PubMed

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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