Abemaciclib

128 interactions 114 explained in plain English 328 cited references
Also sold as: Verzenio Verzenio®
About Abemaciclib

Abemaciclib is used in combination with an aromatase inhibitor such as anastrozole (Arimidex), exemestane (Aromasin), or letrozole (Femara) to treat a certain type of hormone receptor-positive, early breast cancer. Abemaciclib is also used along with fulvestrant (Faslodex) to treat a certain type of hormone receptor-po… Read the full Abemaciclib drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mumps Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Typhoid Vaccine Varicella Virus Vaccine, Live Yellow Fever Vaccine
12 Contraindicated 75 Major 41 Moderate
All (128) Contraindicated (12) Major (75) Moderate (41)

Contraindicated

Abemaciclib Bacillus Of Calmette And Guerin Vaccine, Live Explained An increased risk of infection by the live vaccine Details Abemaciclib Dengue Tetravalent Vaccine, Live Explained An increased risk of infection by the live vaccine Details Abemaciclib Ensitrelvir Explained Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details Abemaciclib Levoketoconazole Recorlev Explained Increased CYP3A4 substrate exposure and an increased risk of sensitive CYP3A4 substrate-related adverse reaction Details Abemaciclib Measles Virus Vaccine, Live Explained An increased risk of infection by the live vaccine Details Abemaciclib Mifepristone Korlym Explained Increased CYP3A4 substrate with NTI exposure Details Abemaciclib Mumps Virus Vaccine, Live Explained An increased risk of infection by the live vaccine Details Abemaciclib Rubella Virus Vaccine, Live Explained An increased risk of infection by the live vaccine Details Abemaciclib Smallpox Monkeypox Vaccine Explained An increased risk of infection by the live vaccine Details Abemaciclib Typhoid Vaccine Typhim VI® Explained An increased risk of infection by the live vaccine Details Abemaciclib Varicella Virus Vaccine, Live Explained An increased risk of infection by the live vaccine Details Abemaciclib Yellow Fever Vaccine Stamaril Explained An increased risk of infection by the live vaccine Details

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