Acetaminophen Injection
28 interactions 489 cited referencesAcetaminophen injection is a pain reliever and fever reducer used to treat mild to moderate pain and fever, or severe pain when combined with opioids. Read the full Acetaminophen Injection drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Moderate
Acetaminophen Injection Acenocoumarol Potentiation of anticoagulant effect Details Acetaminophen Injection Busulfan Busulfex Reduced busulfan clearance Details Acetaminophen Injection Diflunisal Dolobid An increased risk of acetaminophen toxicity (hepatotoxicity) Details Acetaminophen Injection Ethinyl Estradiol Increased ethinyl estradiol exposure and reduced acetaminophen exposure Details Acetaminophen Injection Fosphenytoin Cerebyx Decreased acetaminophen effectiveness and an increased risk of hepatotoxicity Details Acetaminophen Injection Lixisenatide Slowed absorption of acetaminophen Details Acetaminophen Injection Norethindrone Aygestin Increased ethinyl estradiol exposure and reduced acetaminophen exposure Details Acetaminophen Injection Norgestimate Increased ethinyl estradiol exposure and reduced acetaminophen exposure Details Acetaminophen Injection Phenytoin Dilantin Decreased acetaminophen effectiveness and an increased risk of hepatotoxicity Details Acetaminophen Injection Piperaquine Reduced exposure of CYP2E1 substrates Details Acetaminophen Injection Sulfinpyrazone Increased hepatotoxicity in acetaminophen overdose Details Acetaminophen Injection Warfarin Coumadin An increased risk of bleeding Details Acetaminophen Injection Zidovudine Retrovir Neutropenia; acetaminophen toxicity (hepatotoxicity) DetailsNo interactions on this page match that filter — try the next page or clear the filter.
Check another drug
Still have questions about this combination?
Every question gets a real answer from a licensed pharmacist — free, and usually within a day.
Ask the pharmacist