Aliskiren
51 interactions 133 cited referencesAliskiren is used alone or in combination with some medications to treat high blood pressure. Aliskiren is in a class of medications called direct renin inhibitors. It works by decreasing certain natural chemicals that tighten the blood vessels, so blood vessels relax and the heart can pump blood more efficiently. High… Read the full Aliskiren drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Aliskiren Apalutamide Erleada Reduced P-gp substrates exposure Details Aliskiren Berotralstat Orladeyo Increased P-gp substrate exposure Details Aliskiren Capmatinib Tabrecta Increased P-gp substrate exposure and an increased risk of increased adverse reactions Details Aliskiren Cyclosporine Atopica Increased aliskiren exposure and plasma concentrations Details Aliskiren Ensitrelvir Increased risk of P-gp substrate exposure Details Aliskiren Itraconazole Sporanox Increased aliskiren exposure Details Aliskiren Ketoconazole Extina Increased aliskiren exposure and an increased risk of aliskiren-related adverse reactions Details Aliskiren Lenacapavir Sunlenca Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse reactions Details Aliskiren Nirmatrelvir Increased aliskiren exposure Details Aliskiren Potassium Citrate Urocit-K Increased risk of hyperkalemia Details Aliskiren Ritonavir Norvir Increased aliskiren exposure Details Aliskiren Simeprevir Olysio® Increased exposure of P-gp substrate Details Aliskiren Venetoclax Venclexta Increased exposure of P-gp substrate and an increased toxicities of these substrates Details Aliskiren Vimseltinib Romvimza Increased risk of P-gp substrate exposure Details Aliskiren Cyclosporine Injection Atopica Increased aliskiren exposure and plasma concentrations Details Aliskiren Cyclosporine Ophthalmic Cequa Increased aliskiren exposure and plasma concentrations Details Aliskiren Ketoconazole Topical Extina® Foam Increased aliskiren exposure and an increased risk of aliskiren-related adverse reactions Details Aliskiren Lenacapavir Injection Sunlenca Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse reactions Details Aliskiren Lenacapavir Oral Sunlenca Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse reactions DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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