Aliskiren

51 interactions 133 cited references
Also sold as: Tekturna Tekturna®
About Aliskiren

Aliskiren is used alone or in combination with some medications to treat high blood pressure. Aliskiren is in a class of medications called direct renin inhibitors. It works by decreasing certain natural chemicals that tighten the blood vessels, so blood vessels relax and the heart can pump blood more efficiently. High… Read the full Aliskiren drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Contraindicated

Aliskiren Lisinopril Prinivil An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Azilsartan Edarbi An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Azilsartan Medoxomil Edarbi An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Benazepril Lotensin An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Candesartan Atacand An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Captopril Capoten® An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Enalapril Epaned An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Enalaprilat An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Eprosartan Teveten® An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Fosinopril Monopril® An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Irbesartan Avapro An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Losartan Arbli An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Moexipril Univasc® An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Olmesartan Medoxomil Benicar An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Perindopril Aceon An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Quinapril Accupril An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Ramipril Altace An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Sparsentan Filspari An increased aliskiren exposure and an increased risk of hypotension, syncope, hyperkalemia, and changes in renal function (includ... Details Aliskiren Telmisartan Micardis An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Trandolapril Mavik® An increased risk of hyperkalemia, renal impairment, and hypotension Details Aliskiren Valsartan Diovan An increased risk of hyperkalemia, renal impairment and hypotension Details Aliskiren Olmesartan Benicar An increased risk of hyperkalemia, renal impairment, and hypotension Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.