Alogliptin

129 interactions 209 cited references

Also sold as: Nesina Nesina®

About Alogliptin

Alogliptin is used along with diet and exercise to lower blood sugar levels in patients with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Alogliptin is in a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by incre… Read the full Alogliptin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Colchicine Insulin Degludec (Rdna Origin) Injection Abiraterone Abiraterone Acetate Abiraterone Acetate, Micronized Ofloxacin Otic

1 Contraindicated 81 Major 47 Moderate

All (129) Contraindicated (1) Major (81) Moderate (47)

Moderate

Alogliptin Lisinopril Prinivil An increased risk of hypoglycemia Details Alogliptin Atenolol Tenormin Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Acebutolol Sectral® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Benazepril Lotensin An increased risk of hypoglycemia Details Alogliptin Betaxolol Betoptic S Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Bisoprolol Zebeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Captopril Capoten® An increased risk of hypoglycemia Details Alogliptin Carteolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Carvedilol Coreg Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Celiprolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Chlorpropamide Diabinese® An increased risk of hypoglycemia Details Alogliptin Enalapril Epaned An increased risk of hypoglycemia Details Alogliptin Enalaprilat An increased risk of hypoglycemia Details Alogliptin Esmolol Brevibloc Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Fosinopril Monopril® An increased risk of hypoglycemia Details Alogliptin Glecaprevir Altered glycemic control resulting in severe symptomatic hypoglycemia Details Alogliptin Glimepiride Amaryl An increased risk of hypoglycemia Details Alogliptin Glipizide Glucotrol An increased risk of hypoglycemia Details Alogliptin Glyburide DiaBeta® An increased risk of hypoglycemia Details Alogliptin Labetalol Normodyne® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Levobunolol Betagan Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Levothyroxine Ermeza Worsening of glycemic control Details Alogliptin Metipranolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Metoprolol Kapspargo Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Moexipril Univasc® An increased risk of hypoglycemia Details Alogliptin Nadolol Corgard Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Nateglinide Starlix® An increased risk of hypoglycemia Details Alogliptin Nebivolol Bystolic Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Oxprenolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Penbutolol Levatol® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Perindopril Aceon An increased risk of hypoglycemia Details Alogliptin Pibrentasvir Altered glycemic control resulting in severe symptomatic hypoglycemia Details Alogliptin Pindolol Visken® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Practolol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Propranolol Hemangeol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Quinapril Accupril An increased risk of hypoglycemia Details Alogliptin Ramipril Altace An increased risk of hypoglycemia Details Alogliptin Repaglinide Prandin® An increased risk of hypoglycemia Details Alogliptin Sotalol Betapace Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Alogliptin Tenofovir Alafenamide Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.