Asenapine Transdermal Patch

377 interactions 1 explained in plain English 412 cited references

Also sold as: Secuado Secuado®

About Asenapine Transdermal Patch

Asenapine transdermal patches are used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Asenapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain… Read the full Asenapine Transdermal Patch drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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15 Contraindicated 276 Major 86 Moderate

All (377) Contraindicated (15) Major (276) Moderate (86)

Major

Asenapine Transdermal Patch Cannabidiol Epidiolex Increased risk of CNS depression and an increased risk of sedation and somnolence Details Asenapine Transdermal Patch Cannabis An increased risk of CNS depression Details Asenapine Transdermal Patch Carbamazepine Carbatrol An increased risk of CNS depression Details Asenapine Transdermal Patch Carbidopa Lodosyn An increased risk of CNS depression Details Asenapine Transdermal Patch Carbinoxamine Carbzah An increased risk of CNS depression Details Asenapine Transdermal Patch Ceritinib Zykadia An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Cetirizine Aller-Tec Increased risk of CNS depression Details Asenapine Transdermal Patch Chloroquine Aralen® Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Chlorpromazine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Ciprofloxacin An increased asenapine exposure and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Citalopram Celexa An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Clarithromycin Biaxin Increased risk of QT interval prolongation and torsade de pointes Details Asenapine Transdermal Patch Clobazam Onfi Increased risk of sedation Details Asenapine Transdermal Patch Clofazimine An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Clomipramine Anafranil Increased clomiPRAMINE exposure, an increased asenapine exposure, an increased risk of QT interval prolongation and an increased r... Details Asenapine Transdermal Patch Clonazepam Klonopin Increased risk of CNS depression Details Asenapine Transdermal Patch Clothiapine Increased risk of cardiac arrhythmias Details Asenapine Transdermal Patch Clozapine Clozaril Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Codeine Tuzistra XR® (as a combination product containing Chlorpheniramine, Codeine) An increased risk of respiratory and CNS depression Details Asenapine Transdermal Patch Crizotinib Xalkori An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Cyclobenzaprine Amrix An increased risk of CNS depression and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Cyproheptadine An increased risk of CNS depression Details Asenapine Transdermal Patch Dabrafenib Tafinlar An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Daridorexant An increased risk CNS depression Details Asenapine Transdermal Patch Darifenacin Enablex Increased exposure of CYP2D6 substrate and inhibitor and an increased asenapine exposure Details Asenapine Transdermal Patch Dasatinib Phyrago An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Degarelix Firmagon Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Delamanid Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Desflurane Suprane An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Desipramine Norpramin Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Dexmedetomidine Dexased Increased risk of cardiac arrhythmias and increased risk of CNS depression Details Asenapine Transdermal Patch Dextroamphetamine Dexedrine Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Asenapine Transdermal Patch Diazepam Diastat Increased risk of CNS depression Details Asenapine Transdermal Patch Dihydrocodeine Increased risk of respiratory and CNS depression Details Asenapine Transdermal Patch Disopyramide Norpace Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Dofetilide Tikosyn Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Dolasetron Anzemet Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Domperidone Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Donepezil Adlarity Increased risk of QT-interval prolongation and torsade de pointes Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.