Asenapine Transdermal Patch

377 interactions 1 explained in plain English 412 cited references
Also sold as: Secuado Secuado®
About Asenapine Transdermal Patch

Asenapine transdermal patches are used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Asenapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain… Read the full Asenapine Transdermal Patch drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Mesoridazine Metoclopramide Pimozide Piperaquine Bepridil
15 Contraindicated 276 Major 86 Moderate
All (377) Contraindicated (15) Major (276) Moderate (86)

Moderate

Asenapine Transdermal Patch Indapamide An increased risk of hypotension Details Asenapine Transdermal Patch Insulin Afrezza Reduced blood glucose lowering effect of insulin Details Asenapine Transdermal Patch Insulin Lispro, Recombinant Admelog May decrease blood glucose lowering effect of insulin lispro Details Asenapine Transdermal Patch Irbesartan Avapro An increased risk of hypotension Details Asenapine Transdermal Patch Labetalol Normodyne® An increased risk of hypotension Details Asenapine Transdermal Patch Levobunolol Betagan An increased risk of hypotension Details Asenapine Transdermal Patch Lisinopril Prinivil An increased risk of hypotension Details Asenapine Transdermal Patch Losartan Arbli An increased risk of hypotension Details Asenapine Transdermal Patch Methyclothiazide An increased risk of hypotension Details Asenapine Transdermal Patch Metipranolol An increased risk of hypotension Details Asenapine Transdermal Patch Metolazone An increased risk of hypotension Details Asenapine Transdermal Patch Metoprolol Kapspargo An increased risk of hypotension Details Asenapine Transdermal Patch Moexipril Univasc® An increased risk of hypotension Details Asenapine Transdermal Patch Moxisylyte An increased risk of hypotension Details Asenapine Transdermal Patch Nadolol Corgard An increased risk of hypotension Details Asenapine Transdermal Patch Nebivolol Bystolic An increased risk of hypotension Details Asenapine Transdermal Patch Olmesartan Benicar An increased risk of hypotension Details Asenapine Transdermal Patch Oxprenolol An increased risk of hypotension Details Asenapine Transdermal Patch Penbutolol Levatol® An increased risk of hypotension Details Asenapine Transdermal Patch Perindopril Aceon An increased risk of hypotension Details Asenapine Transdermal Patch Phenoxybenzamine Dibenzyline An increased risk of hypotension Details Asenapine Transdermal Patch Phentolamine An increased risk of hypotension Details Asenapine Transdermal Patch Pindolol Visken® An increased risk of hypotension Details Asenapine Transdermal Patch Piretanide An increased risk of hypotension Details Asenapine Transdermal Patch Prazosin Minipress An increased risk of hypotension Details Asenapine Transdermal Patch Propranolol Hemangeol An increased risk of hypotension Details Asenapine Transdermal Patch Quinapril Accupril An increased risk of hypotension Details Asenapine Transdermal Patch Quinethazone An increased risk of hypotension Details Asenapine Transdermal Patch Ramipril Altace An increased risk of hypotension Details Asenapine Transdermal Patch Silodosin Rapaflo An increased risk of hypotension Details Asenapine Transdermal Patch Spirapril An increased risk of hypotension Details Asenapine Transdermal Patch Spironolactone Aldactone An increased risk of hypotension Details Asenapine Transdermal Patch Tamsulosin Flomax An increased risk of hypotension Details Asenapine Transdermal Patch Telmisartan Micardis An increased risk of hypotension Details Asenapine Transdermal Patch Terazosin Hytrin® An increased risk of hypotension Details Asenapine Transdermal Patch Timolol Betimol An increased risk of hypotension Details Asenapine Transdermal Patch Tizanidine An increased risk of CNS depression and sedation Details Asenapine Transdermal Patch Tolazoline An increased risk of hypotension Details Asenapine Transdermal Patch Torsemide Soaanz An increased risk of hypotension Details Asenapine Transdermal Patch Trandolapril Mavik® An increased risk of hypotension Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.