Asenapine Transdermal Patch

377 interactions 1 explained in plain English 412 cited references

Also sold as: Secuado Secuado®

About Asenapine Transdermal Patch

Asenapine transdermal patches are used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Asenapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain… Read the full Asenapine Transdermal Patch drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Mesoridazine Metoclopramide Pimozide Piperaquine Bepridil

15 Contraindicated 276 Major 86 Moderate

All (377) Contraindicated (15) Major (276) Moderate (86)

Major

Asenapine Transdermal Patch Vepdegestrant Veppanu An increased risk of QT interval prolongation and an increased risk of torsade de pointes, polymorphic ventricular tachycardia, ot... Details Asenapine Transdermal Patch Vilanterol An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Vinflunine Increased risk of QT-interval prolongation Details Asenapine Transdermal Patch Voclosporin Lupkynis An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Voriconazole Vfend An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Vorinostat Zolinza Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Ziftomenib Komzifti An increased risk of QT interval prolongation and torsade de pointes Details Asenapine Transdermal Patch Zolpidem Ambien An increased risk of CNS depression, complex sleep behaviors and respiratory depression Details Asenapine Transdermal Patch Zotepine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Zuclopenthixol An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Zuranolone Zurzuvae An increased risk of CNS depression Details

Moderate

Asenapine Transdermal Patch Acebutolol Sectral® An increased risk of hypotension Details Asenapine Transdermal Patch Amiloride An increased risk of hypotension Details Asenapine Transdermal Patch Atenolol Tenormin Explained An increased risk of hypotension Details Asenapine Transdermal Patch Azilsartan Edarbi An increased risk of hypotension Details Asenapine Transdermal Patch Azilsartan Medoxomil Edarbi An increased risk of hypotension Details Asenapine Transdermal Patch Benazepril Lotensin An increased risk of hypotension Details Asenapine Transdermal Patch Bendroflumethiazide An increased risk of hypotension Details Asenapine Transdermal Patch Benzthiazide An increased risk of hypotension Details Asenapine Transdermal Patch Betaxolol Betoptic S An increased risk of hypotension Details Asenapine Transdermal Patch Bisoprolol Zebeta® An increased risk of hypotension Details Asenapine Transdermal Patch Brimonidine Alphagan An increased risk of CNS depression Details Asenapine Transdermal Patch Bumetanide Bumex An increased risk of hypotension Details Asenapine Transdermal Patch Bunazosin An increased risk of hypotension Details Asenapine Transdermal Patch Candesartan Atacand An increased risk of hypotension Details Asenapine Transdermal Patch Captopril Capoten® An increased risk of hypotension Details Asenapine Transdermal Patch Carbachol Isopto Carbachol An increased risk of CNS depression Details Asenapine Transdermal Patch Carteolol An increased risk of hypotension Details Asenapine Transdermal Patch Carvedilol Coreg An increased risk of hypotension Details Asenapine Transdermal Patch Celiprolol An increased risk of hypotension Details Asenapine Transdermal Patch Chlorothiazide Diuril An increased risk of hypotension Details Asenapine Transdermal Patch Chlorthalidone Hemiclor An increased risk of hypotension Details Asenapine Transdermal Patch Clonidine Duraclon Induction or exacerbation of orthostatic regulation disturbances and an increased risk of sedation and somnolence Details Asenapine Transdermal Patch Clopamide An increased risk of hypotension Details Asenapine Transdermal Patch Cyclopenthiazide An increased risk of hypotension Details Asenapine Transdermal Patch Cyclothiazide An increased risk of hypotension Details Asenapine Transdermal Patch Dapiprazole An increased risk of hypotension Details Asenapine Transdermal Patch Diazoxide Proglycem An increased risk of hypotension Details Asenapine Transdermal Patch Doxazosin Cardura An increased risk of hypotension Details Asenapine Transdermal Patch Enalapril Epaned An increased risk of hypotension Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.