Asenapine Transdermal Patch

377 interactions 1 explained in plain English 412 cited references
Also sold as: Secuado Secuado®
About Asenapine Transdermal Patch

Asenapine transdermal patches are used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Asenapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain… Read the full Asenapine Transdermal Patch drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Mesoridazine Metoclopramide Pimozide Piperaquine Bepridil
15 Contraindicated 276 Major 86 Moderate
All (377) Contraindicated (15) Major (276) Moderate (86)

Major

Asenapine Transdermal Patch Ropeginterferon Alfa-2B-Njft Besremi Increased risk of sedation Details Asenapine Transdermal Patch Scopolamine Pamine Increased or potentiated scopolamine effects and an increased risk of CNS depression Details Asenapine Transdermal Patch Selpercatinib Retevmo Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sertindole Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sertraline An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sevoflurane Petrem Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Siponimod Mayzent An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sodium Oxybate Lumryz An increased risk of CNS depression and clinically significant respiratory depression, obtundation, hypotension, profound sedation... Details Asenapine Transdermal Patch Sodium Phosphate OsmoPrep Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sodium Phosphate, Dibasic Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sodium Phosphate, Monobasic Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Solifenacin Vesicare Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sorafenib Nexavar An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sotalol Betapace An increased risk of hypotension and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sufentanil Dsuvia Reduced pulmonary arterial pressure, increased risk for hypotension, profound sedation, respiratory depression, coma, and death Details Asenapine Transdermal Patch Sulpiride An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sultopride Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Sunitinib Sutent Increased risk of QT interval prolongation and an increased risk of torsade de pointes Details Asenapine Transdermal Patch Tacrolimus Astagraf An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Taletrectinib Ibtrozi Increased risk of QT interval prolongation and torsade de pointes Details Asenapine Transdermal Patch Tamoxifen Nolvadex® Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Tapentadol Nucynta An increased risk of respiratory and CNS depression Details Asenapine Transdermal Patch Telaprevir Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Telavancin Vibativ Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Telithromycin Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Tetrabenazine Xenazine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Tolterodine Detrol Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Topiramate Eprontia An increased risk of CNS depression Details Asenapine Transdermal Patch Toremifene Fareston Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Tramadol ConZip Increased traMADol exposure, reduced exposure of the active metabolite and an increased risk of CNS depression Details Asenapine Transdermal Patch Tranylcypromine Parnate An increased risk of CNS depression Details Asenapine Transdermal Patch Trazodone Raldesy Increased risk of CNS depression and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Triclabendazole Egaten An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Trifluoperazine An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Trimipramine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Triptorelin Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Vandetanib Caprelsa An increased risk of QT interval prolongation and torsades de pointes Details Asenapine Transdermal Patch Vardenafil Levitra An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Vemurafenib Zelboraf Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Venlafaxine Increased venlafaxine exposure, an increased asenapine exposure and an increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.