Asenapine Transdermal Patch

377 interactions 1 explained in plain English 412 cited references

Also sold as: Secuado Secuado®

About Asenapine Transdermal Patch

Asenapine transdermal patches are used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Asenapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain… Read the full Asenapine Transdermal Patch drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Mesoridazine Metoclopramide Pimozide Piperaquine Bepridil

15 Contraindicated 276 Major 86 Moderate

All (377) Contraindicated (15) Major (276) Moderate (86)

Major

Asenapine Transdermal Patch Pacritinib Vonjo® An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Paliperidone Erzofri An increased risk of CNS depression, increased risk of QT interval prolongation and torsade de pointes Details Asenapine Transdermal Patch Panobinostat Farydak Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Papaverine Pavacot® Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Paroxetine Paxil Increased PARoxetine exposure, an increased asenapine exposure and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Pasireotide Signifor Increased risk of QT prolongation Details Asenapine Transdermal Patch Pazopanib Votrient Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Pentamidine NebuPent Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Pentazocine Increased risk of respiratory and CNS depression Details Asenapine Transdermal Patch Periciazine Risk of enhanced CNS depression Details Asenapine Transdermal Patch Perphenazine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Phenobarbital Fidoquel An increased risk of QT interval prolongation and an increased risk of CNS depression Details Asenapine Transdermal Patch Pimavanserin Nuplazid An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Pipamperone Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Pitolisant Wakix Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Ponesimod Ponvory An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Posaconazole Noxafil An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Potassium Oxybate Xywav An increased risk of CNS depression and clinically significant respiratory depression, obtundation, hypotension, profound sedation... Details Asenapine Transdermal Patch Pregabalin Bonqat An increased risk of respiratory depression Details Asenapine Transdermal Patch Primidone Mysoline An increased risk of QT interval prolongation and an increased risk of CNS depression Details Asenapine Transdermal Patch Probucol Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Procainamide Procan® Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Prochlorperazine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Promethazine Phenadoz An increased risk of QT interval prolongation and an increased risk of CNS depression Details Asenapine Transdermal Patch Propafenone Rythmol Increased propafenone exposure, an increased asenapine exposure and an increased risk of QT interval prolongation Details Asenapine Transdermal Patch Protriptyline Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Quetiapine Seroquel An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Quinidine Cardioquin® Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Quinine Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Quizartinib Vanflyta An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Ranolazine Aspruzyo Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Relugolix Orgovyx Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Remifentanil Increased risk of CNS depression and an increased risk of hypotension Details Asenapine Transdermal Patch Remimazolam Byfavo Increased risk of profound sedation, respiratory depression, coma, and death Details Asenapine Transdermal Patch Revumenib Revuforj An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Ribociclib Kisqali An increased risk of QT interval prolongation Details Asenapine Transdermal Patch Rilpivirine Edurant An increased risk of QT interval prolongation and torsade de pointes Details Asenapine Transdermal Patch Risperidone Perseris Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Ritonavir Norvir Increased risk of QT interval prolongation Details Asenapine Transdermal Patch Rofecoxib Increased asenapine exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.