Atazanavir

179 interactions 13 explained in plain English

Also sold as: Reyataz

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Irinotecan Lipid Complex Injection Midazolam Nasal Spray Encorafenib Lovastatin Lurasidone Colchicine

18 Contraindicated 134 Major 27 Moderate

All (179) Contraindicated (18) Major (134) Moderate (27)

Major

Atazanavir Glasdegib Daurismo Increased risk of QT interval prolongation Details Atazanavir Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Atazanavir Granisetron Transdermal Patch Sancuso An increased risk of QT interval prolongation Details Atazanavir Granisetron Injection Granisol An increased risk of QT interval prolongation Details Atazanavir Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Atazanavir Hydrocortisone Ala-Cort Increased corticosteroid exposure and an increased risk of corticosteroid-related adverse effects Details Atazanavir Hydrocortisone Injection A-Hydrocort® Increased corticosteroid exposure and an increased risk of corticosteroid-related adverse effects Details Atazanavir Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Atazanavir Ibrutinib Imbruvica Increased ibrutinib exposure Details Atazanavir Ifosfamide Injection Ifex Decreased ifosfamide effectiveness Details Atazanavir Infigratinib Truseltiq Increased infigratinib plasma concentrations Details Atazanavir Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Atazanavir Ivabradine Corlanor Increased exposure of ivabradine and increased risk of QT prolongation Details Atazanavir Lacosamide Injection Motpoly An increased risk of PR interval prolongation, AV block, bradycardia, and ventricular tachyarrhythmia Details Atazanavir Lansoprazole Prevacid Reduced atazanavir exposure, reduced efficacy of atazanavir and development of resistance Details Atazanavir Lenacapavir Injection Sunlenca Increased lenacapavir exposure, increased atazanavir exposure and an increased risk of atazanavir-related adverse reaction Details Atazanavir Lenacapavir Oral Sunlenca Increased lenacapavir exposure, increased atazanavir exposure and an increased risk of atazanavir-related adverse reaction Details Atazanavir Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Atazanavir Letermovir Injection Prevymis Increased CYP3A substrate exposure Details Atazanavir Levofloxacin Levaquin Increased risk of QT interval prolongation Details Atazanavir Levofloxacin Injection Levaquin Increased risk of QT interval prolongation Details Atazanavir Loperamide Diamode Increased loperamide exposure, an increased risk of loperamide-related adverse effects and an increased risk of QT interval prolon... Details Atazanavir Lumateperone Caplyta Increased lumateperone exposure and increased risk of lumateperone-related adverse reactions Details Atazanavir Lurbinectedin Injection Zepzelca Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Atazanavir Mefloquine Lariam® An increased risk of QT interval prolongation Details Atazanavir Metronidazole Flagyl An increased risk of QT interval prolongation Details Atazanavir Metronidazole Injection Flagyl An increased risk of QT interval prolongation Details Atazanavir Metronidazole Topical MetroCream® An increased risk of QT interval prolongation Details Atazanavir Metronidazole Vaginal MetroGel® Vaginal An increased risk of QT interval prolongation Details Atazanavir Mexiletine Mexitil® Increased antiarrhythmics exposure Details Atazanavir Minocycline Amzeeq Decreased atazanavir exposure and plasma concentrations Details Atazanavir Minocycline Topical Amzeeq Decreased atazanavir exposure and plasma concentrations Details Atazanavir Mitapivat Aqvesme Increased mitapivat exposure and reduced CYP3A4 substrate exposure Details Atazanavir Mometasone Asmanex Increased mometasone exposure and an increased risk of mometasone-related adverse reactions Details Atazanavir Mometasone Nasal Spray Nasonex Increased mometasone exposure and an increased risk of mometasone-related adverse reactions Details Atazanavir Mometasone Oral Inhalation Asmanex Increased mometasone exposure and an increased risk of mometasone-related adverse reactions Details Atazanavir Mometasone Topical Elocon® Increased mometasone exposure and an increased risk of mometasone-related adverse reactions Details Atazanavir Moxifloxacin Avelox Increased risk of QT interval prolongation Details Atazanavir Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Atazanavir Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.