Avatrombopag

Name: Avatrombopag Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

35 interactions 1 explained in plain English 249 cited references

Also sold as: Doptelet Doptelet®

About Avatrombopag

Avatrombopag is used to treat thrombocytopenia (a low number of platelets [type of blood cell needed for blood clotting]) in people with chronic (ongoing) liver disease who are scheduled to have a medical or dental procedure to help prevent bleeding complications. It is also used to treat thrombocytopenia in people wit… Read the full Avatrombopag drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ensitrelvir Abametapir Apalutamide Avacopan Letermovir Injection Fluorouracil Topical

1 Contraindicated 29 Major 5 Moderate

All (35) Contraindicated (1) Major (29) Moderate (5)

Contraindicated

Avatrombopag Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.