Chloroquine

332 interactions 586 cited references

Also sold as: Aralen®

About Chloroquine

An antimalarial and amebicide drug used to prevent and treat malaria and amebiasis. Read the full Chloroquine drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Pimozide Saquinavir Levomethadyl Mesoridazine Levoketoconazole

14 Contraindicated 294 Major 23 Moderate 1 Minor

All (332) Contraindicated (14) Major (294) Moderate (23) Minor (1)

Major

Chloroquine Exenatide Bydureon Hypoglycemia Details Chloroquine Famotidine Calmicid Increased risk of QT-interval prolongation Details Chloroquine Felbamate Felbatol Increased risk of QT-interval prolongation Details Chloroquine Fexinidazole An increased risk of QT interval prolongation Details Chloroquine Fingolimod Gilenya Increased risk of QT interval prolongation Details Chloroquine Flecainide Tambocor® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Chloroquine Fluconazole Diflucan An increased risk of QT interval prolongation Details Chloroquine Fluoxetine RECONCILE An increased risk of QT interval prolongation and an increased risk of torsades de pointes Details Chloroquine Formoterol Perforomist Increased risk of QT-interval prolongation Details Chloroquine Foscarnet Foscavir An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Chloroquine Fosfomycin Contepo An increased risk of QT interval prolongation Details Chloroquine Fosphenytoin Cerebyx Increased risk of QT-interval prolongation Details Chloroquine Fostemsavir Rukobia Increased risk of torsade de pointes Details Chloroquine Galantamine Razadyne Increased risk of QT-interval prolongation Details Chloroquine Gatifloxacin Zymaxid An increased risk of QT interval prolongation Details Chloroquine Gemifloxacin Factive An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Chloroquine Gepirone Exxua An increased risk of QT interval prolongation and cardiac arrhythmias Details Chloroquine Gepotidacin Blujepa An increased risk of QT interval prolongation Details Chloroquine Givinostat Duvyzat Increased risk of QT interval prolongation and torsade de pointes Details Chloroquine Glasdegib Daurismo Increased risk of QT interval prolongation Details Chloroquine Glimepiride Amaryl Hypoglycemia Details Chloroquine Glipizide Glucotrol Hypoglycemia Details Chloroquine Glyburide DiaBeta® Hypoglycemia Details Chloroquine Goserelin Increased risk of QT interval prolongation Details Chloroquine Granisetron An increased risk of QT interval prolongation Details Chloroquine Halofantrine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Chloroquine Haloperidol An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Chloroquine Halothane An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Chloroquine Histrelin Supprelin Increased risk of QT interval prolongation Details Chloroquine Hydroquinidine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Chloroquine Hydroxychloroquine Plaquenil An increased risk of seizures and an increased risk of QT interval prolongation Details Chloroquine Hydroxyzine An increased risk of QT interval prolongation Details Chloroquine Ibutilide Corvert Cardiotoxicity (QT interval prolongation, torsades de pointes, cardiac arrest) Details Chloroquine Iloperidone Fanapt An increased risk of QT interval prolongation Details Chloroquine Imipramine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Chloroquine Inotuzumab Ozogamicin Besponsa Increased risk of QT interval prolongation Details Chloroquine Insulin Afrezza Hypoglycemia Details Chloroquine Insulin Aspart, Recombinant Fiasp Hypoglycemia Details Chloroquine Insulin Bovine Hypoglycemia Details Chloroquine Insulin Degludec Tresiba Hypoglycemia Details

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