Darunavir

Major

Darunavir Edoxaban Savaysa Increased edoxaban exposure Details Darunavir Encorafenib Braftovi Increased encorafenib exposure, an increased risk of encorafenib-related adverse reactions, reduced sensitive CYP3A4 substrate exp... Details Darunavir Entrectinib Rozlytrek Increased entrectinib exposure and an increased frequency or severity of adverse reactions Details Darunavir Esmolol Brevibloc Increased beta blocker/antiarrhythmic exposure, increased risk of beta blocker/antiarrhythmic-related adverse effects Details Darunavir Estradiol Delestrogen Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and an increased darunavir exposure Details Darunavir Estradiol Topical Divigel Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and an increased darunavir exposure Details Darunavir Estradiol Transdermal Patch Alora® Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and an increased darunavir exposure Details Darunavir Everolimus Afinitor Increased everolimus exposure and an increased darunavir exposure Details Darunavir Fentanyl Transdermal Patch Duragesic® Increased fentaNYL exposure and an increased risk of prolonged opioid effects Details Darunavir Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Darunavir Fluvastatin Lescol Increased HMG-CoA reductase inhibitors exposure Details Darunavir Hydrocortisone Ala-Cort Increased corticosteroid exposure Details Darunavir Hydrocortisone Injection A-Hydrocort® Increased corticosteroid exposure Details Darunavir Ifosfamide Injection Ifex Decreased ifosfamide effectiveness Details Darunavir Irinotecan Camptosar Increased irinotecan exposure and an increased risk of irinotecan-related adverse events Details Darunavir Irinotecan Injection Camptosar Increased irinotecan exposure and an increased risk of irinotecan-related adverse events Details Darunavir Isradipine DynaCirc® Increased calcium channel blocker exposure and an increased risk of calcium channel blocker-related adverse effects Details Darunavir Ketoconazole Topical Extina® Foam Increased ketoconazole exposure and an increased darunavir exposure Details Darunavir Labetalol Normodyne® Increased beta blocker exposure and an increased risk of beta blocker-related adverse effects Details Darunavir Lefamulin Xenleta Increased lefamulin exposure, an increased risk of lefamulin-related adverse reactions, an increased strong and moderate CYP3A4 in... Details Darunavir Lenacapavir Injection Sunlenca Increased sensitive CYP3A substrate exposure and an increased risk of sensitive CYP3A substrate-mediated adverse reactions Details Darunavir Lenacapavir Oral Sunlenca Increased sensitive CYP3A substrate exposure and an increased risk of sensitive CYP3A substrate-mediated adverse reactions Details Darunavir Letermovir Injection Prevymis Increased CYP3A substrate exposure Details Darunavir Levobunolol Ophthalmic AKBeta® Increased beta blocker exposure and an increased risk of beta blocker-related adverse effects Details Darunavir Levonorgestrel After banger Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and an increased darunavir exposure Details Darunavir Levonorgestrel Intrauterine System Kyleena Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and an increased darunavir exposure Details Darunavir Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Darunavir Lumateperone Caplyta Increased lumateperone exposure and increased risk of lumateperone-related adverse reactions Details Darunavir Lurbinectedin Injection Zepzelca Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Darunavir Medroxyprogesterone Amen® Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and an increased darunavir exposure Details Darunavir Medroxyprogesterone Injection Depo-Provera Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and an increased darunavir exposure Details Darunavir Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Darunavir Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Darunavir Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Darunavir Mitapivat Aqvesme Increased mitapivat exposure and reduced CYP3A4 substrate exposure Details Darunavir Mometasone Asmanex Increased corticosteroid exposure Details Darunavir Mometasone Nasal Spray Nasonex Increased corticosteroid exposure Details Darunavir Mometasone Oral Inhalation Asmanex Increased corticosteroid exposure Details Darunavir Mometasone Topical Elocon® Increased corticosteroid exposure Details Darunavir Nadolol Corgard Increased beta blocker exposure and an increased risk of beta blocker-related adverse effects Details