Desonide Topical

Name: Desonide Topical Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

30 interactions 156 cited references

Also sold as: Desonate® Desowen DesOwen® Verdeso®

About Desonide Topical

Desonide is used to treat the redness, swelling, itching, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body and eczema (a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes). Desonide is… Read the full Desonide Topical drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Desmopressin Mifepristone Aspirin Bemiparin Bupropion Carbamazepine

2 Contraindicated 19 Major 9 Moderate

All (30) Contraindicated (2) Major (19) Moderate (9)

Contraindicated

Desonide Topical Desmopressin DDAVP Increased risk of severe hyponatremia Details Desonide Topical Mifepristone Korlym An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.