Dolasetron Injection

296 interactions 421 cited references

Also sold as: Anzemet Anzemet® Injection

About Dolasetron Injection

Dolasetron injection is used to prevent and treat nausea and vomiting that may occur after surgery. Dolasetron injection should not be used to prevent or treat nausea and vomiting in people receiving cancer chemotherapy medications. Dolasetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It… Read the full Dolasetron Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Levomethadyl Mesoridazine Phenelzine Pimozide Piperaquine

16 Contraindicated 278 Major 1 Moderate 1 Minor

All (296) Contraindicated (16) Major (278) Moderate (1) Minor (1)

Major

Dolasetron Injection Domperidone Increased risk of QT interval prolongation Details Dolasetron Injection Donepezil Adlarity Increased risk of QT-interval prolongation and torsade de pointes Details Dolasetron Injection Dordaviprone An increased risk of QT interval prolongation Details Dolasetron Injection Doxepin Prudoxin Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Droperidol An increased risk of QT interval prolongation Details Dolasetron Injection Duloxetine Increased risk of serotonin syndrome Details Dolasetron Injection Efavirenz An increased risk of QT interval prolongation Details Dolasetron Injection Eletriptan Relpax Increased risk of serotonin syndrome Details Dolasetron Injection Encorafenib Braftovi Increased risk of QT interval prolongation Details Dolasetron Injection Enflurane An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Dolasetron Injection Erythromycin Erythrocin Stearate Increased risk of QT interval prolongation Details Dolasetron Injection Escitalopram Lexapro Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Etrasimod Velsipity Increased risk of transient reduction in heart rate, AV conduction, QT interval prolongation and an increased risk of torsade de p... Details Dolasetron Injection Fenfluramine An increased risk of serotonin syndrome (hypertension, tachycardia, hyperthermia, myoclonus, mental status changes) Details Dolasetron Injection Fentanyl Increased risk of serotonin syndrome Details Dolasetron Injection Fexinidazole An increased risk of QT interval prolongation Details Dolasetron Injection Fingolimod Gilenya Increased risk of QT interval prolongation Details Dolasetron Injection Flecainide Tambocor® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Fluconazole Diflucan An increased risk of QT interval prolongation Details Dolasetron Injection Fluoxetine RECONCILE Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Fluvoxamine Increased risk of serotonin syndrome Details Dolasetron Injection Formoterol Perforomist Increased risk of QT interval prolongation and an increased risk of cardiovascular adverse effects Details Dolasetron Injection Foscarnet Foscavir An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Fosfomycin Contepo An increased risk of QT interval prolongation Details Dolasetron Injection Fosphenytoin Cerebyx An increased risk of QT interval prolongation Details Dolasetron Injection Fostemsavir Rukobia Increased risk of torsade de pointes Details Dolasetron Injection Frovatriptan Frova Increased risk of serotonin syndrome Details Dolasetron Injection Furazolidone Increased risk of serotonin syndrome Details Dolasetron Injection Gatifloxacin Zymaxid An increased risk of QT interval prolongation Details Dolasetron Injection Gemifloxacin Factive An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Gepirone Exxua Increased risk of serotonin syndrome and an increased risk of QT interval prolongation and cardiac arrhythmias Details Dolasetron Injection Gepotidacin Blujepa An increased risk of QT interval prolongation Details Dolasetron Injection Givinostat Duvyzat Increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Injection Glasdegib Daurismo Increased risk of QT interval prolongation Details Dolasetron Injection Goserelin Increased risk of QT interval prolongation Details Dolasetron Injection Granisetron Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Halofantrine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Haloperidol An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Injection Halothane An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.