Dolasetron Injection

296 interactions 421 cited references

Also sold as: Anzemet Anzemet® Injection

About Dolasetron Injection

Dolasetron injection is used to prevent and treat nausea and vomiting that may occur after surgery. Dolasetron injection should not be used to prevent or treat nausea and vomiting in people receiving cancer chemotherapy medications. Dolasetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It… Read the full Dolasetron Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Levomethadyl Mesoridazine Phenelzine Pimozide Piperaquine

16 Contraindicated 278 Major 1 Moderate 1 Minor

All (296) Contraindicated (16) Major (278) Moderate (1) Minor (1)

Major

Dolasetron Injection Histrelin Supprelin Increased risk of QT interval prolongation Details Dolasetron Injection Hydrocodone Hysingla An increased risk of serotonin syndrome Details Dolasetron Injection Hydromorphone Dilaudid Increased risk of serotonin syndrome Details Dolasetron Injection Hydroquinidine Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Hydroxyamphetamine An increased risk of serotonin syndrome Details Dolasetron Injection Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Dolasetron Injection Hydroxytryptophan Increased risk of serotonin syndrome Details Dolasetron Injection Hydroxyzine An increased risk of QT interval prolongation Details Dolasetron Injection Ibutilide Corvert Cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Injection Iloperidone Fanapt An increased risk of QT interval prolongation Details Dolasetron Injection Imipramine Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Inotuzumab Ozogamicin Besponsa Increased risk of QT interval prolongation Details Dolasetron Injection Iproniazid Increased risk of serotonin syndrome Details Dolasetron Injection Isocarboxazid Marplan Increased risk of serotonin syndrome Details Dolasetron Injection Isoflurane Fluriso An increased risk of QT prolongation and torsades de pointes Details Dolasetron Injection Isradipine DynaCirc® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Itraconazole Sporanox An increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Injection Ivabradine Corlanor Increased risk of QT prolongation Details Dolasetron Injection Ivosidenib Tibsovo An increased risk of QT interval prolongation Details Dolasetron Injection Ketoconazole Extina Increased risk of QT interval prolongation Details Dolasetron Injection Kratom An increased risk of serotonin syndrome Details Dolasetron Injection Lacosamide Motpoly An increased risk of PR interval prolongation, AV block, bradycardia, and ventricular tachyarrhythmia Details Dolasetron Injection Lapatinib Tykerb An increased risk of QT interval prolongation Details Dolasetron Injection Lasmiditan Reyvow Increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, mental status changes) Details Dolasetron Injection Lefamulin Xenleta Increased risk of QT interval prolongation Details Dolasetron Injection Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Dolasetron Injection Leuprolide Eligard Increased risk of QT interval prolongation Details Dolasetron Injection Levofloxacin Levaquin Increased risk of QT interval prolongation Details Dolasetron Injection Levomilnacipran Increased risk of serotonin syndrome Details Dolasetron Injection Levorphanol Xyvona An increased risk of serotonin syndrome Details Dolasetron Injection Lidoflazine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Linezolid Zyvox Increased risk of serotonin syndrome Details Dolasetron Injection Lisdexamfetamine Arynta An increased risk of serotonin syndrome Details Dolasetron Injection Lithium Increased risk of serotonin syndrome Details Dolasetron Injection Lofepramine Increased risk of serotonin syndrome Details Dolasetron Injection Lofexidine Increased risk of QT interval prolongation Details Dolasetron Injection Lonafarnib Zokinvy An increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Injection Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Dolasetron Injection Lopinavir An increased risk of QT interval prolongation Details Dolasetron Injection Lorcainide An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.