Dolasetron Injection

296 interactions 421 cited references
Also sold as: Anzemet Anzemet® Injection
About Dolasetron Injection

Dolasetron injection is used to prevent and treat nausea and vomiting that may occur after surgery. Dolasetron injection should not be used to prevent or treat nausea and vomiting in people receiving cancer chemotherapy medications. Dolasetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It… Read the full Dolasetron Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Levomethadyl Mesoridazine Phenelzine Pimozide Piperaquine
16 Contraindicated 278 Major 1 Moderate 1 Minor
All (296) Contraindicated (16) Major (278) Moderate (1) Minor (1)

Major

Dolasetron Injection Lorcaserin Increased risk of serotonin syndrome Details Dolasetron Injection Lumefantrine An increased risk of QT interval prolongation Details Dolasetron Injection Macimorelin Increased risk of QT interval prolongation Details Dolasetron Injection Mavorixafor Xolremdi An increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Injection Mefloquine Lariam® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Melitracen Increased risk of serotonin syndrome Details Dolasetron Injection Meperidine Demerol Increased risk of serotonin syndrome Details Dolasetron Injection Metaxalone Skelaxin Increased risk of serotonin syndrome Details Dolasetron Injection Methadone Diskets Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Methamphetamine Desoxyn An increased risk of serotonin syndrome Details Dolasetron Injection Methylene Blue Provayblue Increased risk of serotonin syndrome Details Dolasetron Injection Metronidazole Flagyl An increased risk of QT interval prolongation Details Dolasetron Injection Mifepristone Korlym An increased risk of QT interval prolongation Details Dolasetron Injection Milnacipran Savella Increased risk of serotonin syndrome Details Dolasetron Injection Milsaperidone An increased risk of QT interval prolongation Details Dolasetron Injection Mirtazapine Mirataz Increased risk of serotonin syndrome, an increased risk of QT interval prolongation and an increased risk of torsades de pointes Details Dolasetron Injection Mobocertinib Exkivity An increased risk of QT interval prolongation Details Dolasetron Injection Moclobemide Increased risk of serotonin syndrome Details Dolasetron Injection Morphine Increased risk of serotonin syndrome Details Dolasetron Injection Morphine Sulfate Liposome Increased risk of serotonin syndrome Details Dolasetron Injection Moxifloxacin Avelox Increased risk of QT interval prolongation Details Dolasetron Injection Nalbuphine Increased risk of serotonin syndrome Details Dolasetron Injection Naratriptan Increased risk of serotonin syndrome Details Dolasetron Injection Nefazodone Increased risk of serotonin syndrome Details Dolasetron Injection Nelfinavir Viracept Increased risk of QT interval prolongation Details Dolasetron Injection Nilotinib An increased risk of QT interval prolongation Details Dolasetron Injection Norfloxacin An increased risk of QT interval prolongation Details Dolasetron Injection Nortriptyline Increased risk of serotonin syndrome Details Dolasetron Injection Octreotide Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Ofloxacin Floxin® An increased risk of QT interval prolongation Details Dolasetron Injection Olanzapine An increased risk of QT interval prolongation Details Dolasetron Injection Oliceridine Olinvyk Increased risk of serotonin syndrome Details Dolasetron Injection Olodaterol Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Dolasetron Injection Ondansetron An increased risk of serotonin syndrome and QT interval prolongation Details Dolasetron Injection Opipramol Increased risk of serotonin syndrome Details Dolasetron Injection Osilodrostat Isturisa Increased risk of QT interval prolongation Details Dolasetron Injection Osimertinib Tagrisso Increased risk of QT interval prolongation Details Dolasetron Injection Oxaliplatin Increased risk of QT-interval prolongation Details Dolasetron Injection Oxycodone Oxaydo Increased risk of serotonin syndrome Details Dolasetron Injection Oxymorphone Increased risk of serotonin syndrome Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.