Dolasetron Injection

296 interactions 421 cited references
Also sold as: Anzemet Anzemet® Injection
About Dolasetron Injection

Dolasetron injection is used to prevent and treat nausea and vomiting that may occur after surgery. Dolasetron injection should not be used to prevent or treat nausea and vomiting in people receiving cancer chemotherapy medications. Dolasetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It… Read the full Dolasetron Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Levomethadyl Mesoridazine Phenelzine Pimozide Piperaquine
16 Contraindicated 278 Major 1 Moderate 1 Minor
All (296) Contraindicated (16) Major (278) Moderate (1) Minor (1)

Major

Dolasetron Injection Ozanimod Additive effects on heart rate Details Dolasetron Injection Pacritinib Vonjo® An increased risk of QT interval prolongation Details Dolasetron Injection Paliperidone Erzofri An increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Injection Palonosetron An increased risk of serotonin syndrome Details Dolasetron Injection Panobinostat Farydak Increased risk of QT interval prolongation Details Dolasetron Injection Paroxetine Paxil Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Pasireotide Signifor Increased risk of QT prolongation Details Dolasetron Injection Pazopanib Votrient An increased risk of QT interval prolongation Details Dolasetron Injection Pentamidine NebuPent An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Pentazocine Increased risk of serotonin syndrome Details Dolasetron Injection Phenobarbital Fidoquel An increased risk of QT interval prolongation Details Dolasetron Injection Pimavanserin Nuplazid An increased risk of QT interval prolongation Details Dolasetron Injection Pirmenol Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Pitolisant Wakix Increased risk of QT interval prolongation Details Dolasetron Injection Ponesimod Ponvory An increased risk of QT interval prolongation Details Dolasetron Injection Posaconazole Noxafil An increased risk of QT interval prolongation Details Dolasetron Injection Prajmaline Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Primidone Mysoline An increased risk of QT interval prolongation Details Dolasetron Injection Probucol An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Procainamide Procan® Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Procarbazine Increased risk of serotonin syndrome Details Dolasetron Injection Prochlorperazine Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Promethazine Phenadoz An increased risk of QT interval prolongation Details Dolasetron Injection Propafenone Rythmol An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Protriptyline Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Quetiapine Seroquel An increased risk of QT interval prolongation Details Dolasetron Injection Quinidine Cardioquin® Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Quinine An increased risk of QT interval prolongation Details Dolasetron Injection Quizartinib Vanflyta An increased risk of QT interval prolongation Details Dolasetron Injection Ranolazine Aspruzyo An increased risk of QT interval prolongation Details Dolasetron Injection Rasagiline Azilect Increased risk of serotonin syndrome Details Dolasetron Injection Relugolix Orgovyx Increased risk of QT interval prolongation Details Dolasetron Injection Remifentanil Increased risk of serotonin syndrome Details Dolasetron Injection Revumenib Revuforj An increased risk of QT interval prolongation Details Dolasetron Injection Ribociclib Kisqali An increased risk of QT interval prolongation Details Dolasetron Injection Rilpivirine Edurant An increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Injection Risperidone Perseris An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Injection Rizatriptan Increased risk of serotonin syndrome Details Dolasetron Injection Selegiline Anipryl Increased risk of serotonin syndrome Details Dolasetron Injection Selpercatinib Retevmo Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.