Dolasetron Injection

296 interactions 421 cited references
Also sold as: Anzemet Anzemet® Injection
About Dolasetron Injection

Dolasetron injection is used to prevent and treat nausea and vomiting that may occur after surgery. Dolasetron injection should not be used to prevent or treat nausea and vomiting in people receiving cancer chemotherapy medications. Dolasetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It… Read the full Dolasetron Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Levomethadyl Mesoridazine Phenelzine Pimozide Piperaquine
16 Contraindicated 278 Major 1 Moderate 1 Minor
All (296) Contraindicated (16) Major (278) Moderate (1) Minor (1)

Major

Dolasetron Injection Sematilide Cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Injection Sertindole An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Injection Sertraline Increased risk of serotonin syndrome and an increased risk of QT interval prolongation Details Dolasetron Injection Sevoflurane Petrem Increased risk of QT interval prolongation Details Dolasetron Injection Sibutramine Increased risk of serotonin syndrome Details Dolasetron Injection Siponimod Mayzent An increased risk of QT interval prolongation Details Dolasetron Injection Sodium Phosphate OsmoPrep An increased risk of QT interval prolongation Details Dolasetron Injection Sodium Phosphate, Dibasic An increased risk of QT interval prolongation Details Dolasetron Injection Sodium Phosphate, Monobasic An increased risk of QT interval prolongation Details Dolasetron Injection Solifenacin Vesicare An increased risk of QT interval prolongation Details Dolasetron Injection Sorafenib Nexavar An increased risk of QT interval prolongation Details Dolasetron Injection Sotalol Betapace An increased risk of QT interval prolongation Details Dolasetron Injection Spiramycin An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection St John's Wort Increased risk of serotonin syndrome Details Dolasetron Injection Sufentanil Dsuvia Increased risk of serotonin syndrome Details Dolasetron Injection Sulfamethoxazole Sustain An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Sulpiride An increased risk of QT interval prolongation Details Dolasetron Injection Sultopride An increased risk of cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Injection Sumatriptan Imitrex Increased risk of serotonin syndrome Details Dolasetron Injection Sunitinib Sutent An increased risk of QT interval prolongation Details Dolasetron Injection Tacrolimus Astagraf An increased risk of QT interval prolongation Details Dolasetron Injection Taletrectinib Ibtrozi Increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Injection Tamoxifen Nolvadex® An increased risk of QT interval prolongation Details Dolasetron Injection Tapentadol Nucynta Increased risk of serotonin syndrome Details Dolasetron Injection Tedisamil Cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Injection Tedizolid Phosphate Sivextro An increased risk of serotonin syndrome Details Dolasetron Injection Telavancin Vibativ An increased risk of QT interval prolongation Details Dolasetron Injection Telithromycin An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Tetrabenazine Xenazine An increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Injection Tianeptine Increased risk of serotonin syndrome Details Dolasetron Injection Toremifene Fareston An increased risk of QT interval prolongation, ventricular tachycardia or an increased risk of torsade de pointes Details Dolasetron Injection Tramadol ConZip Increased risk of serotonin syndrome Details Dolasetron Injection Trazodone Raldesy Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Triclabendazole Egaten An increased risk of QT interval prolongation Details Dolasetron Injection Trifluoperazine Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Trimethoprim Primsol An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Injection Trimipramine Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Injection Triptorelin Increased risk of QT interval prolongation Details Dolasetron Injection Tryptophan Increased risk of serotonin syndrome Details Dolasetron Injection Vandetanib Caprelsa An increased risk of QT interval prolongation and Torsades de pointes Details

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