Ethynodiol

Name: Ethynodiol Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

46 interactions 2 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Isotretinoin Lixisenatide Injection Colesevelam Penicillin V Potassium Meropenem Injection Bexarotene Topical

40 Major 6 Moderate

All (46) Major (40) Moderate (6)

Moderate

Ethynodiol Amitriptyline Elavil Explained Attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Details Ethynodiol Clopidogrel Plavix Reduced clopidogrel active metabolite exposure and reduced platelet inhibition Details Ethynodiol Diazepam Nasal Spray Valtoco Diazepam toxicity (CNS depression, hypotension) Details Ethynodiol Diazepam Rectal Diastat Diazepam toxicity (CNS depression, hypotension) Details Ethynodiol Dofetilide Tikosyn Increased dofetilide exposure Details Ethynodiol Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.