Furosemide Injection

241 interactions 649 cited references

Also sold as: Disal Furoscix Furoscix® Lasix Lasix® Salix - substance

About Furosemide Injection

Furosemide injection is used in adults and children who cannot take oral medications or in emergency situations to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart failure, pulmonary edema (excess fluid in the lungs), kidney, and liver disease. Furosem… Read the full Furosemide Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Methenamine Desmopressin Vonoprazan Dexibuprofen Dasabuvir Dapagliflozin

2 Contraindicated 195 Major 41 Moderate 3 Minor

All (241) Contraindicated (2) Major (195) Moderate (41) Minor (3)

Major

Furosemide Injection Cephalexin Keflet® Tablets Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Chloral Hydrate An increased risk of flushing, sweating attacks, restlessness, nausea and an increased blood pressure and tachycardia Details Furosemide Injection Chlorpropamide Diabinese® An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Choline Salicylate Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Cisplatin An increased ototoxicity and an increased risk of nephrotoxicity Details Furosemide Injection Clonixin Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Codeine Tuzistra XR® (as a combination product containing Chlorpheniramine, Codeine) Reduced diuretic efficacy Details Furosemide Injection Dapagliflozin Farxiga An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Dasabuvir Increased furosemide exposure Details Furosemide Injection Dexibuprofen Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Dexketoprofen Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Diazoxide Proglycem An increased risk of hyperglycemia and hyperuricemia Details Furosemide Injection Dichlorphenamide Increased OAT1 substrate exposure Details Furosemide Injection Diclofenac Aleve Arthritis Pain Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Diflunisal Dolobid An increased risk of salicylate toxicity and reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Digitoxin Digitoxin toxicity (nausea, vomiting, cardiac arrhythmias) Details Furosemide Injection Dihydrocodeine Reduced efficacy of diuretics Details Furosemide Injection Dipyrone Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Droxicam Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Dulaglutide Trulicity An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Enalapril Epaned An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Furosemide Injection Enalaprilat An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Furosemide Injection Epinephrine An increased risk of cardiac arrhythmias Details Furosemide Injection Eprosartan Teveten® Severe hypotension and deterioration in renal function, including renal failure Details Furosemide Injection Ethacrynic Acid Edecrin An increased risk of ototoxicity Details Furosemide Injection Etodolac Lodine Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Etofenamate Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Etoricoxib Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Exenatide Bydureon An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Felbinac Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Fenoprofen Fenopron Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Fentanyl Reduced diuretic efficacy Details Furosemide Injection Fepradinol Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Feprazone Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Fexinidazole Increased exposure of OAT1/OAT3 substrate Details Furosemide Injection Floctafenine Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Flufenamic Acid Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Flurbiprofen Ansaid Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Formoterol Perforomist An increased risk of ECG changes or hypokalemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.