Itraconazole

Name: Itraconazole Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

206 interactions 14 explained in plain English

Also sold as: Sporanox Tolsura

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Nisoldipine Disopyramide Lovastatin Dihydroergotamine Injection Finerenone Irinotecan Lipid Complex Injection

22 Contraindicated 174 Major 10 Moderate

All (206) Contraindicated (22) Major (174) Moderate (10)

Moderate

Itraconazole Esomeprazole Injection Nexium Reduced itraconazole exposure Details Itraconazole Guanfacine Intuniv Increased guanfacine exposure Details Itraconazole Lansoprazole Prevacid Reduced itraconazole exposure Details Itraconazole Meloxicam Alloxate Reduced meloxicam exposure Details Itraconazole Meloxicam Injection Alloxate Reduced meloxicam exposure Details Itraconazole Nizatidine Axid® Reduced itraconazole exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.