Itraconazole

Major

Itraconazole Lumateperone Caplyta Increased lumateperone exposure and an increased risk of lumateperone-related adverse reactions Details Itraconazole Lurbinectedin Injection Zepzelca Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Itraconazole Macitentan Opsumit Increased macitentan exposure Details Itraconazole Maraviroc Selzentry Increased maraviroc exposure Details Itraconazole Mefloquine Lariam® An increased risk of QT interval prolongation and torsade de pointes Details Itraconazole Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Itraconazole Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Itraconazole Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Itraconazole Metronidazole Flagyl An increased risk of QT interval prolongation Details Itraconazole Metronidazole Injection Flagyl An increased risk of QT interval prolongation Details Itraconazole Metronidazole Topical MetroCream® An increased risk of QT interval prolongation Details Itraconazole Metronidazole Vaginal MetroGel® Vaginal An increased risk of QT interval prolongation Details Itraconazole Midostaurin Rydapt Increased midostaurin exposure Details Itraconazole Mirvetuximab Soravtansine-Gynx Injection Elahere Increased unconjugated DM4 exposure and an increased risk of mirvetuximab soravtansine-gynx adverse reactions Details Itraconazole Mitapivat Aqvesme Increased mitapivat exposure and an increased risk of mitapivat-related adverse reactions Details Itraconazole Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Itraconazole Moxifloxacin Avelox Increased risk of QT interval prolongation Details Itraconazole Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Itraconazole Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details Itraconazole Nadolol Corgard Increased nadolol exposure and an increased risk of nadolol adverse effects Details Itraconazole Naldemedine Symproic Increased CYP3A4/P-gp substrate exposure and an increased risk of CYP3A4/P-gp substrate-related adverse effects Details Itraconazole Nateglinide Starlix® Increased CYP3A4 substrate exposure and an increased risk of CYP3A4 substrate-related adverse effects Details Itraconazole Neratinib Nerlynx Increased neratinib exposure and risk of toxicity Details Itraconazole Nevirapine Viramune Reduced itraconazole exposure and reduced efficacy of itraconazole Details Itraconazole Nicardipine Cardene An increased risk of congestive heart failure Details Itraconazole Nifedipine Adalat® Increased NIFEdipine exposure and an increased risk of hypotension, bradycardia, or acute renal injury Details Itraconazole Nimodipine Nimotop An increased risk of congestive heart failure Details Itraconazole Nintedanib Ofev Increased nintedanib exposure and an increased risk of nintedanib-related adverse effects Details Itraconazole Octreotide Bynfezia An increased risk of QT interval prolongation and torsade de pointes Details Itraconazole Octreotide Injection Bynfezia An increased risk of QT interval prolongation and torsade de pointes Details Itraconazole Ofloxacin Floxin® An increased risk of QT interval prolongation and torsade de pointes Details Itraconazole Ofloxacin Ophthalmic Ocuflox An increased risk of QT interval prolongation and torsade de pointes Details Itraconazole Ofloxacin Otic Floxin® Otic An increased risk of QT interval prolongation and torsade de pointes Details Itraconazole Olaparib Lynparza Increased olaparib exposure Details Itraconazole Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Itraconazole Oxaliplatin Injection Eloxatin® Increased risk of QT-interval prolongation Details

Moderate

Itraconazole Abemaciclib Verzenio Explained Increased abemaciclib plasma concentration Details Itraconazole Dexlansoprazole Dexilant Reduced itraconazole exposure Details Itraconazole Didanosine Videx® Decreased itraconazole effectiveness Details Itraconazole Esomeprazole Nexium Reduced itraconazole exposure Details