Levoketoconazole

185 interactions 11 explained in plain English

Also sold as: Recorlev Recorlev®

About Levoketoconazole

Levoketoconazole is used to treat high levels of cortisol (a hormone produced by your adrenal glands) in patients with Cushing's syndrome (a condition in which the body produces too much cortisol) and who have failed surgery or cannot have surgery to treat this condition. Levoketoconazole is in a class of medications c… Read the full Levoketoconazole drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Metronidazole Injection Mefloquine Hydroxychloroquine Oxaliplatin Injection Clindamycin Topical Chloroquine

103 Contraindicated 82 Major

All (185) Contraindicated (103) Major (82)

Major

Levoketoconazole Busulfan Injection Busulfex Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Captopril Capoten® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Caspofungin Injection Cancidas Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Cefadroxil Duricef® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Cefdinir Omnicef® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Clofarabine Injection Clolar Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Clopidogrel Plavix Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Dactinomycin Cosmegen Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Danazol Danocrine® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Deferasirox Exjade Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Dexlansoprazole Dexilant Reduced levoketoconazole exposure Details Levoketoconazole Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Diclofenac Transdermal Patch Flector Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Disulfiram Antabuse Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Enalapril Epaned Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Entecavir Baraclude Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Epoprostenol Flolan Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Erlotinib Tarceva Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Esomeprazole Nexium Reduced levoketoconazole exposure Details Levoketoconazole Esomeprazole Injection Nexium Reduced levoketoconazole exposure Details Levoketoconazole Ethambutol Myambutol Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Etodolac Lodine Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Febuxostat Uloric Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Fenoprofen Fenopron Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Flutamide Eulexin Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Fulvestrant Faslodex Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Fulvestrant Injection Faslodex Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Ganciclovir Cytovene® Oral Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Ganciclovir Injection Cytovene® I.V.® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Ganciclovir Ophthalmic Zirgan Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Gemcitabine Avgemsi Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Gemcitabine Injection Avgemsi Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Gemtuzumab Ozogamicin Injection Mylotarg Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Glimepiride Amaryl Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Golimumab Injection Simponi Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Hydroxyurea Droxia Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Interferon Beta-1A Intramuscular Injection Avonex Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Interferon Beta-1A Subcutaneous Injection Avonex Increased risk of serious hepatotoxicity and drug-induced liver injury Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.