Levonorgestrel Intrauterine System
211 interactions 370 cited referencesLevonorgestrel intrauterine system (Liletta, Kyleena, Mirena, Skyla) is used to prevent pregnancy. The Mirena brand intrauterine system is also used to treat heavy menstrual bleeding in women who want to use an intrauterine system to prevent pregnancy. Levonorgestrel is in a class of medications called hormonal contrac… Read the full Levonorgestrel Intrauterine System drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Moderate
Levonorgestrel Intrauterine System Perampanel FYCOMPA Decreased contraceptive effectiveness Details Levonorgestrel Intrauterine System Protriptyline Attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Details Levonorgestrel Intrauterine System Selegiline Anipryl An increase in selegiline oral bioavailability and an increased risk of selegiline adverse reactions Details Levonorgestrel Intrauterine System Succinylcholine Anectine Prolongation of neuromuscular blockade Details Levonorgestrel Intrauterine System Tacrine An increased risk of tacrine adverse effects Details Levonorgestrel Intrauterine System Temazepam Restoril Reduced temazepam exposure and reduced efficacy of temazepam Details Levonorgestrel Intrauterine System Teriflunomide Aubagio Increased levonorgestrel exposure Details Levonorgestrel Intrauterine System Triazolam Halcion Triazolam toxicity (excessive sedation, confusion) Details Levonorgestrel Intrauterine System Trimipramine Attenuation of antidepressant effectiveness; tricyclic toxicity (drowsiness, hypotension, akathisia) Details Levonorgestrel Intrauterine System Zolmitriptan Zomig An increased risk of zolmitriptan adverse effects DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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