Lumateperone
188 interactions 331 cited referencesLumateperone is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Lumateperone is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substan… Read the full Lumateperone drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Lumateperone Vemurafenib Zelboraf Reduced lumateperone exposure Details Lumateperone Verapamil Calan Increased lumateperone exposure and increased risk of lumateperone-related adverse reactions Details Lumateperone Vinblastine Velban® Reduced lumateperone exposure Details Lumateperone Voriconazole Vfend Increased lumateperone exposure, an increased lumateperone-related adverse reactions, an increased voriconazole exposure and an in... Details Lumateperone Voxelotor Oxbryta Increased lumateperone exposure and increased risk of lumateperone-related adverse reactions Details Lumateperone Zanubrutinib Brukinsa Reduced lumateperone exposure Details Lumateperone Nafcillin Injection Unipen® Injection Reduced lumateperone exposure DetailsModerate
Lumateperone Sertraline An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Dofetilide Tikosyn Increased dofetilide exposure Details Lumateperone Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Lumateperone Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Lumateperone Citalopram Celexa An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Desvenlafaxine Pristiq An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Duloxetine An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Escitalopram Lexapro An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Fluoxetine RECONCILE An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Fluvoxamine An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Kratom Increased CYP3A substrate exposure Details Lumateperone Levomilnacipran An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Lumefantrine Increased artemether/lumefantrine exposure and an increased risk of potentiated QT prolongation Details Lumateperone Mavacamten Camzyos Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Lumateperone Milnacipran Savella An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Paroxetine Paxil An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Rilzabrutinib Wayrilz Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Lumateperone Sibutramine An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Venlafaxine An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Vilazodone Viibryd An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions Details Lumateperone Vortioxetine Trintellix An increased risk for serotonin reuptake inhibitor (SRI)-associated adverse reactions DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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