Metoclopramide Nasal Spray

Name: Metoclopramide Nasal Spray Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

247 interactions 689 cited references

Also sold as: Gimoti Gimoti®

About Metoclopramide Nasal Spray

Metoclopramide nasal spray is used to relieve symptoms caused by slow stomach emptying in people who have diabetes. These symptoms include nausea, vomiting, heartburn, loss of appetite, and feeling of fullness that lasts long after meals. Metoclopramide is in a class of medications called prokinetic agents. It works by… Read the full Metoclopramide Nasal Spray drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Iloperidone Imipramine Levomilnacipran Loxapine Zuclopenthixol Mavorixafor

63 Contraindicated 174 Major 6 Moderate 4 Minor

All (247) Contraindicated (63) Major (174) Moderate (6) Minor (4)

Moderate

Metoclopramide Nasal Spray Mivacurium Prolonged neuromuscular block Details Metoclopramide Nasal Spray Oxybutynin Ditropan Decreased metoclopramide efficacy Details Metoclopramide Nasal Spray Succinylcholine Anectine Prolonged neuromuscular blockade Details

Minor

Metoclopramide Nasal Spray Cimetidine Tagamet Decreased cimetidine effectiveness Details Metoclopramide Nasal Spray Lithospermum Decreased effectiveness of DOPamine antagonists Details Metoclopramide Nasal Spray Vitex Decreased effectiveness of DOPamine antagonists Details Metoclopramide Nasal Spray Zalcitabine An increased risk of decreased zalcitabine efficacy Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.