Metronidazole Vaginal

242 interactions 832 cited references

Also sold as: MetroGel® Vaginal Nuvessa Nuvessa® Vandazole Vandazole®

About Metronidazole Vaginal

Metronidazole is used to treat vaginal infections such as bacterial vaginosis (an infection caused from too much of certain bacteria in the vagina). Metronidazole is in a class of medications called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. Read the full Metronidazole Vaginal drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine Thioridazine

15 Contraindicated 214 Major 13 Moderate

All (242) Contraindicated (15) Major (214) Moderate (13)

Major

Metronidazole Vaginal Desipramine Norpramin An increased risk of QT interval prolongation Details Metronidazole Vaginal Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Metronidazole Vaginal Dexmedetomidine Dexased Increased risk of cardiac arrhythmias Details Metronidazole Vaginal Disopyramide Norpace An increased risk of QT interval prolongation Details Metronidazole Vaginal Dofetilide Tikosyn An increased risk of QT interval prolongation Details Metronidazole Vaginal Dolasetron Anzemet An increased risk of QT interval prolongation Details Metronidazole Vaginal Domperidone An increased risk of QT interval prolongation Details Metronidazole Vaginal Donepezil Adlarity Increased risk of QT-interval prolongation and torsade de pointes Details Metronidazole Vaginal Dordaviprone An increased risk of QT interval prolongation Details Metronidazole Vaginal Doxepin Prudoxin An increased risk of QT interval prolongation Details Metronidazole Vaginal Doxifluridine Increased exposure of 5-fluorouracil Details Metronidazole Vaginal Droperidol An increased risk of QT interval prolongation Details Metronidazole Vaginal Ebastine An increased risk of QT interval prolongation Details Metronidazole Vaginal Efavirenz An increased risk of QT interval prolongation Details Metronidazole Vaginal Encorafenib Braftovi Increased risk of QT interval prolongation Details Metronidazole Vaginal Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Metronidazole Vaginal Eribulin Halaven An increased risk of QT interval prolongation Details Metronidazole Vaginal Erythromycin Erythrocin Stearate An increased risk of QT interval prolongation Details Metronidazole Vaginal Escitalopram Lexapro An increased risk of QT interval prolongation Details Metronidazole Vaginal Etrasimod Velsipity Increased risk of transient reduction in heart rate, AV conduction, QT interval prolongation and an increased risk of torsade de p... Details Metronidazole Vaginal Exenatide Bydureon Reduced oral antibiotics absorption and reduced efficacy of oral antibiotics Details Metronidazole Vaginal Famotidine Calmicid An increased risk of QT interval prolongation Details Metronidazole Vaginal Felbamate Felbatol An increased risk of QT interval prolongation Details Metronidazole Vaginal Fexinidazole An increased risk of QT interval prolongation Details Metronidazole Vaginal Fingolimod Gilenya An increased risk of QT interval prolongation Details Metronidazole Vaginal Flecainide Tambocor® An increased risk of QT interval prolongation Details Metronidazole Vaginal Fluconazole Diflucan An increased risk of QT interval prolongation Details Metronidazole Vaginal Fluorouracil Adrucil Increased exposure of 5-fluorouracil Details Metronidazole Vaginal Fluoxetine RECONCILE An increased risk of QT interval prolongation Details Metronidazole Vaginal Formoterol Perforomist An increased risk of QT interval prolongation Details Metronidazole Vaginal Foscarnet Foscavir An increased risk of QT interval prolongation Details Metronidazole Vaginal Fosfomycin Contepo An increased risk of QT interval prolongation Details Metronidazole Vaginal Fosphenytoin Cerebyx An increased risk of fosphenytoin toxicity, reduced metroNIDAZOLE exposure and an increased risk of QT interval prolongation Details Metronidazole Vaginal Fostemsavir Rukobia Increased risk of torsade de pointes Details Metronidazole Vaginal Galantamine Razadyne An increased risk of QT interval prolongation Details Metronidazole Vaginal Gatifloxacin Zymaxid An increased risk of QT interval prolongation Details Metronidazole Vaginal Gemifloxacin Factive An increased risk of QT interval prolongation Details Metronidazole Vaginal Gepirone Exxua An increased risk of QT interval prolongation and cardiac arrhythmias Details Metronidazole Vaginal Gepotidacin Blujepa An increased risk of QT interval prolongation Details Metronidazole Vaginal Givinostat Duvyzat Increased risk of QT interval prolongation and torsade de pointes Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.