Metronidazole Vaginal

242 interactions 832 cited references
Also sold as: MetroGel® Vaginal Nuvessa Nuvessa® Vandazole Vandazole®
About Metronidazole Vaginal

Metronidazole is used to treat vaginal infections such as bacterial vaginosis (an infection caused from too much of certain bacteria in the vagina). Metronidazole is in a class of medications called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. Read the full Metronidazole Vaginal drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine Thioridazine
15 Contraindicated 214 Major 13 Moderate
All (242) Contraindicated (15) Major (214) Moderate (13)

Contraindicated

Metronidazole Vaginal Amprenavir An increased risk of propylene glycol toxicity (seizures, tachycardia, lactic acidosis, renal toxicity, hemolysis) Details Metronidazole Vaginal Bepridil An increased risk of QT interval prolongation Details Metronidazole Vaginal Cisapride Propulsid® Increased risk of QT interval prolongation Details Metronidazole Vaginal Disulfiram Antabuse An increased risk of psychotic reactions Details Metronidazole Vaginal Dronabinol Marinol Disulfiram-like reaction Details Metronidazole Vaginal Dronedarone Multaq Increased risk of QT interval prolongation Details Metronidazole Vaginal Levoketoconazole Recorlev An increased risk of QT interval prolongation and an increased risk of torsade de pointes Details Metronidazole Vaginal Mesoridazine An increased risk of QT interval prolongation Details Metronidazole Vaginal Pimozide An increased risk of QT interval prolongation Details Metronidazole Vaginal Piperaquine An increased risk of QT interval prolongation Details Metronidazole Vaginal Saquinavir An increased risk of QT interval prolongation Details Metronidazole Vaginal Sparfloxacin An increased risk of QT interval prolongation Details Metronidazole Vaginal Terfenadine An increased risk of QT interval prolongation Details Metronidazole Vaginal Thioridazine An increased risk of QT interval prolongation Details Metronidazole Vaginal Ziprasidone Geodon An increased risk of QT interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.