Metronidazole Vaginal

242 interactions 832 cited references

Also sold as: MetroGel® Vaginal Nuvessa Nuvessa® Vandazole Vandazole®

About Metronidazole Vaginal

Metronidazole is used to treat vaginal infections such as bacterial vaginosis (an infection caused from too much of certain bacteria in the vagina). Metronidazole is in a class of medications called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. Read the full Metronidazole Vaginal drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine Thioridazine

15 Contraindicated 214 Major 13 Moderate

All (242) Contraindicated (15) Major (214) Moderate (13)

Major

Metronidazole Vaginal Glasdegib Daurismo Increased risk of QT interval prolongation Details Metronidazole Vaginal Goserelin Increased risk of QT interval prolongation Details Metronidazole Vaginal Granisetron An increased risk of QT interval prolongation Details Metronidazole Vaginal Halofantrine An increased risk of QT interval prolongation Details Metronidazole Vaginal Haloperidol An increased risk of QT interval prolongation Details Metronidazole Vaginal Histrelin Supprelin Increased risk of QT interval prolongation Details Metronidazole Vaginal Hydroquinidine An increased risk of QT interval prolongation Details Metronidazole Vaginal Hydroxychloroquine Plaquenil An increased risk of seizures and an increased risk of QT interval prolongation Details Metronidazole Vaginal Hydroxyzine An increased risk of QT interval prolongation Details Metronidazole Vaginal Ibutilide Corvert An increased risk of QT interval prolongation Details Metronidazole Vaginal Iloperidone Fanapt An increased risk of QT interval prolongation Details Metronidazole Vaginal Imipramine An increased risk of QT interval prolongation Details Metronidazole Vaginal Inotuzumab Ozogamicin Besponsa Increased risk of QT interval prolongation Details Metronidazole Vaginal Isoflurane Fluriso An increased risk of QT interval prolongation and torsade de pointes Details Metronidazole Vaginal Itraconazole Sporanox An increased risk of QT interval prolongation Details Metronidazole Vaginal Ivabradine Corlanor An increased risk of QT interval prolongation Details Metronidazole Vaginal Ivosidenib Tibsovo An increased risk of QT interval prolongation Details Metronidazole Vaginal Ketoconazole Extina An increased risk of QT interval prolongation Details Metronidazole Vaginal Lapatinib Tykerb An increased risk of QT interval prolongation Details Metronidazole Vaginal Lefamulin Xenleta Increased risk of QT interval prolongation Details Metronidazole Vaginal Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Metronidazole Vaginal Leuprolide Eligard Increased risk of QT interval prolongation Details Metronidazole Vaginal Levofloxacin Levaquin An increased risk of QT interval prolongation Details Metronidazole Vaginal Lithium Increased lithium exposure and an increased risk of lithium toxicity (weakness, tremor, excessive thirst, confusion) Details Metronidazole Vaginal Lofexidine Increased risk of QT interval prolongation Details Metronidazole Vaginal Lonafarnib Zokinvy An increased risk of QT interval prolongation and torsade de pointes Details Metronidazole Vaginal Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Metronidazole Vaginal Lumefantrine An increased risk of QT interval prolongation Details Metronidazole Vaginal Macimorelin Increased risk of QT interval prolongation Details Metronidazole Vaginal Mavorixafor Xolremdi An increased risk of QT interval prolongation and torsade de pointes Details Metronidazole Vaginal Mebendazole Emverm Increased risk of Stevens-Johnson syndrome and/or toxic epidermal necrolysis Details Metronidazole Vaginal Mefloquine Lariam® An increased risk of QT interval prolongation Details Metronidazole Vaginal Methadone Diskets An increased risk of QT interval prolongation Details Metronidazole Vaginal Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Metronidazole Vaginal Methotrimeprazine An increased risk of QT interval prolongation Details Metronidazole Vaginal Mifepristone Korlym An increased risk of QT interval prolongation Details Metronidazole Vaginal Milsaperidone An increased risk of QT interval prolongation Details Metronidazole Vaginal Mirtazapine Mirataz An increased risk of QT interval prolongation Details Metronidazole Vaginal Mizolastine An increased risk of QT interval prolongation Details Metronidazole Vaginal Mobocertinib Exkivity An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.