Mexiletine
82 interactions 465 cited referencesMexiletine is used to treat certain types of ventricular arrhythmias (abnormal heart rhythms). Mexiletine is in a class of medications called antiarrhythmics. It works by blocking certain electrical signals in the heart to stabilize the heart rhythm. Read the full Mexiletine drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Contraindicated
Mexiletine Fezolinetant Increased fezolinetant exposure Details Mexiletine Levomethadyl An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Mexiletine Mavorixafor Xolremdi Increased CYP2D6 substrate exposure and an increased risk of CYP2D6 substrate-related adverse events Details Mexiletine Vernakalant Increased risk of atrial flutter and other cardiovascular events Details Mexiletine Viloxazine Qelbree Increased exposure of CYP2D6 substrates that are CYP1A2 sensitive or NTI substrates and an increased risk of CYP2D6 substrates tha... DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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