Mexiletine
82 interactions 465 cited referencesMexiletine is used to treat certain types of ventricular arrhythmias (abnormal heart rhythms). Mexiletine is in a class of medications called antiarrhythmics. It works by blocking certain electrical signals in the heart to stabilize the heart rhythm. Read the full Mexiletine drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Moderate
Mexiletine Agomelatine Increased exposure to agomelatine Details Mexiletine Cannabis Reduced CYP1A2 substrate exposure Details Mexiletine Cobicistat Tybost Increased mexiletine exposure Details Mexiletine Darunavir Increased antiarrhythmic exposure and an increased risk of antiarrhythmic-related adverse effects Details Mexiletine Fluvoxamine Increased mexiletine exposure Details Mexiletine Lorcaserin Increased mexiletine plasma concentrations Details Mexiletine Mirabegron Myrbetriq Increased mexiletine plasma concentrations Details Mexiletine Obeticholic Acid Ocaliva Increased exposure to CYP1A2 substrate Details Mexiletine Propafenone Rythmol An increased risk of mexiletine toxicity (cardiac arrhythmia) Details Mexiletine Propranolol Hemangeol Increased propranolol exposure Details Mexiletine Rasagiline Azilect Increased rasagiline plasma concentrations and risk of rasagiline adverse effects Details Mexiletine Rifapentine Priftin Decreased antiarrhythmic effectiveness Details Mexiletine Ritonavir Norvir Increased mexiletine serum concentrations and potential toxicity (nausea, dizziness, cardiac arrhythmias) DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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