Niacin

Name: Niacin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

24 interactions 109 cited references

Also sold as: Endur-Acin Endur-Amide Niacor Niacor® Niaspan Niaspan® Nicolar® Slo-Niacin Slo-Niacin®

About Niacin

Niacin is a B-complex vitamin used to lower cholesterol and triglycerides and prevent niacin deficiency. Read the full Niacin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Cerivastatin Insulin Icodec-Abae Rosuvastatin Pitavastatin Levoketoconazole Insulin Aspart, Recombinant

14 Major 6 Moderate 4 Minor

All (24) Major (14) Moderate (6) Minor (4)

Moderate

Niacin Fluvastatin Lescol An increased risk of myopathy or rhabdomyolysis Details Niacin Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details Niacin Insulin Afrezza May decrease blood glucose lowering effect of insulin Details Niacin Insulin Lispro, Recombinant Admelog May decrease blood glucose lowering effect of insulin lispro Details Niacin Pravastatin Pravachol An increased risk of myopathy and rhabdomyolysis Details Niacin Warfarin Coumadin Increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.