Perindopril

195 interactions 540 cited references
Also sold as: Aceon Aceon® Prestalia® (as a combination product containing Amlodipine, Perindopril)
About Perindopril

Perindopril is an ACE inhibitor medication used to treat high blood pressure. Read the full Perindopril drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Moderate

Perindopril Meloxicam Alloxate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Meloxicam Injection Alloxate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Metformin Fortamet® An increased risk of hypoglycemia Details Perindopril Miglitol Glyset® An increased risk of hypoglycemia Details Perindopril Nabumetone Relafen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Naproxen Aleve Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Nateglinide Starlix® An increased risk of hypoglycemia Details Perindopril Aceclofenac Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Acemetacin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Albiglutide An increased risk of hypoglycemia Details Perindopril Amtolmetin Guacil Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Asenapine Saphris An increased risk of hypotension Details Perindopril Bemetizide Reduction of blood pressure Details Perindopril Bendroflumethiazide Reduction of blood pressure Details Perindopril Benzthiazide Reduction of blood pressure Details Perindopril Bromfenac Bromsite Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Bufexamac Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Bumetanide Bumex Postural hypotension (first dose) Details Perindopril Bupivacaine Exparel Bradycardia and hypotension with loss of consciousness Details Perindopril Bupivacaine Liposome Exparel Bradycardia and hypotension with loss of consciousness Details Perindopril Buthiazide Reduction of blood pressure Details Perindopril Celecoxib Celebrex Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Chlorothiazide Diuril Reduction of blood pressure Details Perindopril Chlorpropamide Diabinese® An increased risk of hypoglycemia Details Perindopril Chlorthalidone Hemiclor Reduction of blood pressure Details Perindopril Choline Salicylate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Clonixin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Clopamide Reduction of blood pressure Details Perindopril Cyclopenthiazide Reduction of blood pressure Details Perindopril Cyclothiazide Reduction of blood pressure Details Perindopril Dexibuprofen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Dexketoprofen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Diclofenac Aleve Arthritis Pain Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Diflunisal Dolobid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Dipyrone Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Droxicam Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Dulaglutide Trulicity An increased risk of hypoglycemia Details Perindopril Ethacrynic Acid Edecrin Postural hypotension (first dose) Details Perindopril Etofenamate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Perindopril Etoricoxib Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details

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