Rosiglitazone

45 interactions 2 explained in plain English
Also sold as: Avandia®
About Rosiglitazone

Rosiglitazone is used along with a diet and exercise program and sometimes with one or more other medications to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Rosiglitazone is in a class of medications called thiazolidine… Read the full Rosiglitazone drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Octreotide Chloroquine Gemifloxacin Ofloxacin Otic Entacapone Insulin Glulisine (Rdna Origin) Injection
25 Major 20 Moderate
All (45) Major (25) Moderate (20)

Moderate

Rosiglitazone Lisinopril Prinivil Explained An increased risk of hypoglycemia Details Rosiglitazone Atenolol Tenormin Explained Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Acebutolol Sectral® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Benazepril Lotensin An increased risk of hypoglycemia Details Rosiglitazone Betaxolol Betoptic S Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Betaxolol Ophthalmic Betoptic® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Bisoprolol Zebeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Captopril Capoten® An increased risk of hypoglycemia Details Rosiglitazone Enalapril Epaned An increased risk of hypoglycemia Details Rosiglitazone Esmolol Brevibloc Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Fosinopril Monopril® An increased risk of hypoglycemia Details Rosiglitazone Labetalol Normodyne® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Leflunomide Arava Increased rosiglitazone exposure Details Rosiglitazone Levobunolol Ophthalmic AKBeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Levothyroxine Ermeza Worsening of glycemic control Details Rosiglitazone Moexipril Univasc® An increased risk of hypoglycemia Details Rosiglitazone Nadolol Corgard Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Nebivolol Bystolic Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Penbutolol Levatol® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Rosiglitazone Perindopril Aceon An increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.