Sevelamer

Name: Sevelamer Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

4 interactions

Also sold as: RenaGel Renagel® Renvela Renvela®

About Sevelamer

Sevelamer is used to control high blood levels of phosphorus in people with chronic kidney disease who are on dialysis (medical treatment to clean the blood when the kidneys are not working properly). Sevelamer is in a class of medications called phosphate binders. It binds phosphorus that you get from foods in your di… Read the full Sevelamer drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

4 Moderate

All (4) Moderate (4)

Moderate

Sevelamer Cyclosporine Injection Atopica Reduced efficacy of oral cyclosporine Details Sevelamer Cyclosporine Ophthalmic Cequa Reduced efficacy of oral cyclosporine Details Sevelamer Levothyroxine Ermeza Reduced efficacy of levothyroxine and an increased risk of hypothyroidism Details Sevelamer Liothyronine Cytomel Decreased liothyronine effectiveness Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.