Trandolapril

Name: Trandolapril Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

62 interactions 1 explained in plain English

Also sold as: Mavik®

About Trandolapril

Trandolapril is used alone or in combination with other medications to treat high blood pressure. It is also used to improve survival in patients with heart failure after a heart attack. Trandolapril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemi… Read the full Trandolapril drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aliskiren Aspirin Mercaptopurine Everolimus Irbesartan Cyclosporine Injection

1 Contraindicated 16 Major 45 Moderate

All (62) Contraindicated (1) Major (16) Moderate (45)

Moderate

Trandolapril Metformin Fortamet® An increased risk of hypoglycemia Details Trandolapril Miglitol Glyset® An increased risk of hypoglycemia Details Trandolapril Nabumetone Relafen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Trandolapril Naproxen Aleve Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Trandolapril Nateglinide Starlix® An increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.