Trandolapril

Name: Trandolapril Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

62 interactions 1 explained in plain English

Also sold as: Mavik®

About Trandolapril

Trandolapril is used alone or in combination with other medications to treat high blood pressure. It is also used to improve survival in patients with heart failure after a heart attack. Trandolapril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemi… Read the full Trandolapril drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aliskiren Aspirin Mercaptopurine Everolimus Irbesartan Cyclosporine Injection

1 Contraindicated 16 Major 45 Moderate

All (62) Contraindicated (1) Major (16) Moderate (45)

Contraindicated

Trandolapril Aliskiren Tekturna An increased risk of hyperkalemia, renal impairment, and hypotension Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.