Valdecoxib

Name: Valdecoxib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

94 interactions 5 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Nasal Spray Ketorolac Ketorolac Injection Ketorolac Ophthalmic Apixaban Pemetrexed Injection

4 Contraindicated 60 Major 28 Moderate 2 Minor

All (94) Contraindicated (4) Major (60) Moderate (28) Minor (2)

Minor

Valdecoxib Diazepam Nasal Spray Valtoco Increased plasma exposure to diazepam and increased sedative side effects of diazepam Details Valdecoxib Diazepam Rectal Diastat Increased plasma exposure to diazepam and increased sedative side effects of diazepam Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.