Drug & supplement interaction

Abs Diet + Entrectinib

Entrectinib brand name: Rozlytrek.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Abs Diet and Entrectinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Abs Diet and Entrectinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Entrectinib and Abs Diet in our sources. This does not guarantee that the combination is completely free of risk — research on Abs Diet alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Abs Diet at all — not against Entrectinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Abs Diet is an eating pattern rather than something you take. Ask your pharmacist or doctor before changing how you eat while on a prescribed medicine: some medicines are dosed around meals, and a change in diet can change how they work. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Abs Diet safety at a glance

Abs Diet overall Use caution It is an eating and exercise plan; general principles are reasonable but individual needs vary, so get personalized advice.
Pregnancy Use caution Pregnancy is not the time to follow a weight-loss diet; talk with your doctor about nutrition needs.
Breastfeeding Use caution Nursing increases calorie and nutrient needs, so check with a healthcare provider before dieting.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Entrectinib and Abs Diet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Entrectinib’s Own FDA Label Lists

This is not an interaction — none of it involves Abs Diet. These are the most notable effects listed in the ADVERSE REACTIONS section of Entrectinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you follow Abs Diet and take the medicine. 10 of them are worth acting on rather than waiting out — marked below.

  • Loss of vision Worth acting on
  • Bone thinning Worth acting on
  • Muscle weakness Worth acting on
  • Memory problems Worth acting on
  • Dehydration Worth acting on
  • Trouble swallowing Worth acting on
  • High potassium Worth acting on
  • Unsteadiness Worth acting on
  • Blood clots Worth acting on
  • Hallucinations Worth acting on

Showing the 10 most notable of 53 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Entrectinib. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,653 voluntary FDA FAERS reports for Entrectinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Abs Diet’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Abs Diet side to compare — that is a limit of the record, not a statement that Abs Diet has no side effects.

Everything else you take

See Every Supplement That Interacts With Entrectinib

This page covers Abs Diet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Entrectinib page lists 175 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Beer (major) and Cesium (major).

By severity: 11 major · 127 moderate · 37 minor.

From our pharmacist’s overview on the Entrectinib page

“Grapefruit tops my worry list for anyone taking entrectinib (Rozlytrek), a targeted cancer therapy cleared by the liver enzyme CYP3A4. 121 of the 175 supplement ingredients on this page can shift how that enzyme handles the drug.”

Reviewed by 2 · Jul 18, 2026

Open the Entrectinib interaction page

How much people look this up

Where Abs Diet and Entrectinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Abs Diet
Steady interest

#1,076 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Entrectinib
Top half

#1,026 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Abs Diet is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Abs Diet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Abs Diet and Entrectinib records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Eating pattern

About Abs Diet

What is Abs Diet?

  • Weight loss
  • Belly fat reduction
  • Building lean muscle
  • General fitness and nutrition
  • Heart health support

The Abs Diet is a diet and exercise program created by a magazine editor, not a dietary supplement, herb, or pill. It promotes whole foods, regular exercise, and a balanced eating pattern, which can support weight loss for some people, but it is a lifestyle plan rather than a product you take. Talk with a doctor, pharmacist, or dietitian before starting any new diet program.

Diet program and book; meal plans and recipes

An interaction check asks whether these two react with each other — it does not ask whether Abs Diet is a good idea for someone in your situation. Here is what our Abs Diet record says about it on its own.

Abs Diet: dosing

There is no "dose" for the Abs Diet because it is a meal-and-exercise plan, not a supplement. The program is described in its books, which lay out food choices, meal timing, sample menus, and workout routines.If you want to follow it, use the official book or program materials and adjust portions to your own calorie and nutrient needs. A registered dietitian or your pharmacist can help you tailor the plan and make sure it is safe alongside any medical conditions or medicines.

From our Abs Diet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Abs Diet monograph & all interactions
Medication

About Entrectinib

What Is Entrectinib Used For?

Brand name: Rozlytrek

Rozlytrek (entrectinib) is used to treat adult patients with ROS1-positive metastatic non-small cell lung cancer (NSCLC), as confirmed by an FDA-approved test. It is also approved for adult and pediatric patients older than 1 month of age who have solid tumors — any cancer type — that carry an NTRK gene fusion detected by an FDA-approved test, provided the tumor has no known acquired resistance mutation, is metastatic or cannot be surgically removed without severe harm, and has progressed after prior treatment or has no satisfactory alternative therapy.

The NTRK gene fusion approval in solid tumors was granted under accelerated approval, meaning it is based on tumor response rates. Continued approval may depend on results from confirmatory clinical trials.

Most-Reported Side Effects for Entrectinib

From FAERS, the FDA’s public side-effect reporting system (1,653 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dizziness 150 reports
Disease progression 117 reports
Taste disorder 71 reports
Constipation 66 reports
Blood creatinine increased 62 reports
See full Entrectinib drug information
Keep checking

Other Drugs & Abs Diet

Browse every other medication we’ve checked against Abs Diet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Abs Diet References

The 2 sources that drive our Abs Diet monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Abs Diet is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Choosing a Safe and Successful Weight-Loss Program — NIDDK (NIH) Source
  2. Losing Weight — MedlinePlus (NIH) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Following Abs Diet While Taking Entrectinib: Common Questions

Is it safe to follow Abs Diet while taking Entrectinib?
We do not list a known interaction between Abs Diet and Entrectinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Entrectinib interact with any supplements?
Yes. Entrectinib has documented interactions with 175 supplements in our database — Abs Diet is not one of them. The Entrectinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Entrectinib and Abs Diet?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.