Drug & supplement interaction

Ajuga Nipponensis + Tolnaftate

Tolnaftate brand name: Tinactin.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Ajuga Nipponensis and Tolnaftate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Ajuga Nipponensis and Tolnaftate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tolnaftate and Ajuga Nipponensis in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Ajuga Nipponensis at all — not against Tolnaftate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Ajuga Nipponensis safety at a glance

Ajuga Nipponensis overall Not established There is not enough reliable human data to judge its safety.
Pregnancy Avoid Safety has not been studied, so it is best avoided during pregnancy.
Breastfeeding Avoid No safety data exists for breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tolnaftate and Ajuga Nipponensis? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Ajuga Nipponensis Itself Has Been Linked To

This is not an interaction — nothing below involves Tolnaftate. It is the side-effect record for Ajuga Nipponensis on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Ajuga Nipponensis, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Kidney problems Worth acting on Additional detail

    “Orally, Ajuga nipponensis has been reported to cause acute renal failure. An adult male with pre-existing liver cirrhosis developed acute renal failure after ingesting approximately 45 grams of whole Ajuga nipponensis.”

    Ajuga Nipponensis · Natural Medicines adverse-effect record, reported in cirrhosis.

    1 source cited
    1. 14070. Liao SC, Chiu TF, Chen JC, Lin CC. Ajuga nipponensis Makino poisoning. Clin Toxicol (Phila) 2005;43:583-5.
  • Diarrhea / Vomiting / Nausea Additional detail

    “Orally, Ajuga nipponensis has been reported to cause diarrhea, nausea, and vomiting.”

    Ajuga Nipponensis · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 14070. Liao SC, Chiu TF, Chen JC, Lin CC. Ajuga nipponensis Makino poisoning. Clin Toxicol (Phila) 2005;43:583-5.

Everything above comes from the Natural Medicines adverse-effect record for Ajuga Nipponensis — expand a row for the licensed statement it rests on. We haven’t matched Tolnaftate to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Tolnaftate.

From our Q&A

Questions About Ajuga Nipponensis or Tolnaftate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Ajuga Nipponensis or Tolnaftate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Tolnaftate

This page covers Ajuga Nipponensis only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tolnaftate page lists 20 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 12 minor.

From our pharmacist’s overview on the Tolnaftate page

“For anyone using tolnaftate (Tinactin), the antifungal in athlete's foot creams and sprays, activated charcoal is the interaction to understand before all others. It holds the only major rating among the 20 ingredients on file, since charcoal binds many medicines and can lower how much reaches the body, even drugs not given by mouth.”

Reviewed by 2 · Jul 18, 2026

Open the Tolnaftate interaction page

How much people look this up

Where Ajuga Nipponensis and Tolnaftate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Ajuga Nipponensis
Steady interest

#1,295 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tolnaftate
Steady interest

#1,701 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ajuga Nipponensis reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Ajuga Nipponensis and Tolnaftate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Ajuga Nipponensis

What is Ajuga Nipponensis?

Ajuga Nipponensis
  • Cough and respiratory symptoms
  • Sore throat
  • Fever
  • Inflammation
  • Traditional general wellness

Ajuga nipponensis is a perennial plant from East Asia used in traditional medicine for cough and respiratory complaints. There is very little human research to confirm any health benefits, so its effectiveness and safety remain largely unknown. Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or taking other medicines.

Ajuga nipponensis · Lamiaceae · Whole plant, leaves, and aerial parts · Dried herb, tea, traditional decoctions, extracts

An interaction check asks whether these two react with each other — it does not ask whether Ajuga Nipponensis is a good idea for someone in your situation. Here is what our Ajuga Nipponensis record says about it on its own.

Ajuga Nipponensis: dosing

There is no established or standardized dose for Ajuga nipponensis. Scientists have not determined a safe and effective amount for any condition.If you choose to use a product that contains it, follow the directions on the label and do not exceed them.

From our Ajuga Nipponensis monograph — the full record covers uses, side effects and every documented interaction.

Read the full Ajuga Nipponensis monograph & all interactions
Medication

About Tolnaftate

What Is Tolnaftate Used For?

Brand name: Tinactin

Tolnaftate treats common fungal skin infections — specifically athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). It also helps relieve the itching, cracking, burning, scaling, redness, and soreness that come with these infections.

Several products also help prevent athlete's foot from coming back with regular daily use. Note that tolnaftate is not effective on the scalp or nails — though some patch products are applied around the nail and cuticle area to address skin surrounding the nail.

Most-Reported Side Effects for Tolnaftate

From FAERS, the FDA’s public side-effect reporting system (1,403 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 88 reports
Nausea 86 reports
Dyspnea 80 reports
Diarrhea 73 reports
Anxiety 69 reports
See full Tolnaftate drug information
Keep checking

Other Drugs & Ajuga Nipponensis

Browse every other medication we’ve checked against Ajuga Nipponensis — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Ajuga Nipponensis References

The 1 references that drive our Ajuga Nipponensis monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Liao SC, Chiu TF, Chen JC, Lin CC. Ajuga nipponensis Makino poisoning. Clin Toxicol (Phila) 2005;43:583-5.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Ajuga Nipponensis and Tolnaftate Together: Common Questions

Is it safe to take Ajuga Nipponensis with Tolnaftate?
We do not list a known interaction between Ajuga Nipponensis and Tolnaftate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Tolnaftate interact with any supplements?
Yes. Tolnaftate has documented interactions with 20 supplements in our database — Ajuga Nipponensis is not one of them. The Tolnaftate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tolnaftate and Ajuga Nipponensis?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.